Results 121 to 130 of about 110,909 (237)

Unleashing the Power of Machine Learning in Nanomedicine Formulation Development

Advanced Functional Materials, EarlyView.
A random forest machine learning model is able to make predictions on nanoparticle attributes of different nanomedicines (i.e. lipid nanoparticles, liposomes, or PLGA nanoparticles) based on microfluidic formulation parameters. Machine learning models are based on a database of nanoparticle formulations, and models are able to generate unique solutions
Thomas L. Moore, Cristiano Pesce, Antonietta Greco, Claudia Pisante, Greta Avancini, Valentina Di Francesco, Yosi Shamay, Paolo Decuzzi   +7 more
wiley   +1 more source

Modified Factor VIII and Factor IX recombinant products

HemaSphere, 2018
Elena Santagostino, Maria Elisa Mancuso
doaj   +1 more source

Characteristics and Treatment Patterns of Patients with Haemophilia B Receiving Recombinant Coagulation Factor IX. [PDF]

J Clin Med
Park YS, Hwang TJ, Park SK, Choi EJ, Park JA, Baek HJ, Lyu CJ, Lee JH, Kim MK, Kim JY, Lee SA, Park B, Kim DH, Chung SB, Nam CM, Lee Y, Yoo KY.   +16 more
europepmc   +1 more source

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

Prothrombin Time and Coagulation Factor IX as Hemostatic Risk Markers for Legg- Calvé-Perthes Disease. [PDF]

Clin Appl Thromb Hemost, 2023
Hernández-Zamora E, Rodríguez-Olivas AO, Rosales-Cruz E, Galicia-Alvarado MA, Zavala-Hernández C, Reyes-Maldonado E.   +5 more
europepmc   +1 more source

Smarter Sensors Through Machine Learning: Historical Insights and Emerging Trends across Sensor Technologies

Advanced Functional Materials, EarlyView.
This review highlights how machine learning (ML) algorithms are employed to enhance sensor performance, focusing on gas and physical sensors such as haptic and strain devices. By addressing current bottlenecks and enabling simultaneous improvement of multiple metrics, these approaches pave the way toward next‐generation, real‐world sensor applications.
Kichul Lee, Osman Gul, Yeongjae Kwon, Jaeseok Jeong, Seokjoo Cho, Jihyeon Ahn, Jehee Yu, Cheolmin Kim, Donho Lee, Hyeonseok Han, Byeongju Lee, Jungrak Choi, Ji‐Hwan Ha, Yongrok Jeong, Kyungnam Kang, Ali Javey, Junseong Ahn, Inkyu Park   +17 more
wiley   +1 more source

Extravascular factor IX after gene therapy in hemophilia B, does it matter? [PDF]

Res Pract Thromb Haemost
Van Thillo Q, Hermans C.
europepmc   +1 more source

Solar Heating Enhanced Selective Recovery of Metal Ions Through Flowing Electrodes Enabled by Hybrid Carbon Nanostructures

Advanced Functional Materials, EarlyView.
A new electrochemical system based on a microporous hybrid of carbon nanoplatelets and nanotubes to selectively capture Ni2+ from wastewater is constructed. The system temperature rises rapidly when irradiated with sunlight, which enhances the Ni2+ removal rate by 250% and the selectivity by 53%, and the energy consumption is also reduced by 51 ...
Ziquan Wang, Jiaqi Chen, Qiuru Lin, Mingxing Liang, Bo Yang, Yantao Chen, Minjun Kim, Yusuke Yamauchi, Stephen J. Eichhorn, Zhiqun Lin, Magdalena Titirici, Libo Deng   +11 more
wiley   +1 more source

Tailored collagen binding of albumin-fused hyperactive coagulation factor IX dictates in vivo distribution and functional properties. [PDF]

Nat Commun
Aaen KH, Testa MF, Nilsen J, Tarantino R, Canepari C, Benedusi M, Benjakul S, Nyquist-Andersen M, Herigstad ML, Cantore A, Valacchi G, Sandlie I, Bernardi F, Pinotti M, Branchini A, Andersen JT.   +15 more
europepmc   +1 more source

Operando Temperature Sensing at the Actual Electrocatalytic Interface by Nanodiamond Quantum Sensors

Advanced Functional Materials, EarlyView.
By integrating a wide‐field microscope with a custom‐designed electrolyzer, nanoscale temperature changes can be recorded in situ during the electrolysis process without interfering with ongoing electrochemical reactions. This method establishes a correlation between the interface temperature and specific electrochemical reactions, making the measured ...
Zan Li, Hui Wang, Mingzhong Ai, Yao Gao, Xinyi Feng, Junchen Ye, Ying Wang, Quan Li   +7 more
wiley   +1 more source