Results 181 to 190 of about 14,739,736 (367)

Carbonic anhydrase IX downregulation linked to disruption of HIF-1, NFκB and STAT3 pathways as a new mechanism of ibuprofen anti-cancer effect.

PLoS ONE
Numerous studies have highlighted the anti-cancer effects of nonsteroidal anti-inflammatory drugs (NSAIDs), although the underlying mechanisms remain unclear.
Katarina Grossmannova, Petra Belvoncikova, Barbora Puzderova, Veronika Simko, Lucia Csaderova, Jaromir Pastorek, Monika Barathova   +6 more
doaj   +1 more source

Systemic delivery of factor IX messenger RNA for protein replacement therapy

Proceedings of the National Academy of Sciences of the United States of America, 2017
Suvasini Ramaswamy, Nina Tonnu, K. Tachikawa, P. Limphong, J. Vega, P. Karmali, P. Chivukula, I. Verma   +7 more
semanticscholar   +1 more source

Serum uric acid levels in older adults: Associations with clinical outcomes and implications for reference intervals in those aged 70 years and over

Arthritis Care &Research, Accepted Article.
Objectives Reports have linked both high and low serum uric acid (SUA) levels to adverse health outcomes. This study aimed to establish a reference interval for SUA in older adults and assessed its association with clinically relevant outcomes in relatively healthy, community‐dwelling individuals aged 70 and older.
Amanda J Rickard, Cammie Tran, Hans G Schneider, Flavia M Cicuttini, Anita E Wluka, Ego Seeman, Johannes T Neumann, Md Nazmul Karim, Zhen Zhou, Sultana Monira Hussain, David P Q Clark, Daniel Clayton‐Chubb, Andrew M Tonkin, Lawrence J Beilin, Robyn L Woods, John J McNeil   +15 more
wiley   +1 more source

A commentary on the differences in pharmacokinetics between recombinant and plasma-derived factor IX and their implications for dosing [PDF]

, 2011
Sven Björkman
openalex   +1 more source

Low‐factor consumption for major surgery in haemophilia B with long‐acting recombinant glycoPEGylated factor IX

Haemophilia, 2017
Miguel A. Escobar, Ramin Tehranchi, F. A. Karim, U. Çalişkan, P. Chowdary, T. Colberg, Paul Giangrande, A. Giermasz, M. E. Mancuso, M. Serban, Woei Tsay, Johnny Mahlangu   +11 more
semanticscholar   +1 more source

Economic Burden of Rheumatoid Arthritis in Low‐ and Middle‐Income Countries: Systematic Review and Meta‐Analysis

Arthritis Care &Research, EarlyView.
Objective The aim of this systematic review was to synthesize the economic impact of rheumatoid arthritis (RA) on households, health systems, and society in low‐ and middle‐income countries (LMICs). Methods Electronic databases such as PubMed, Web of Science, and CINAHL were searched using keywords related to RA and cost of illness.
Tadesse Gebrye, Chidozie E. Mbada, Clara T. Fatoye, Faatihah Niyi‐Odumosu, Ushotanefe Useh, Zalmai Hakimi, Francis Fatoye   +6 more
wiley   +1 more source

Estudio familiar de las hemofilias A y B: 5 años de experiencia en la detección de portadoras Family study of hemophilia A and B: 5 years of experience in carrier detection

Revista Cubana de Hematología, Inmunología y Hemoterapia, 2010
La hemofilia se caracteriza por ser una enfermedad congénita del trastorno de la coagulación y constituye un desorden recesivo ligado al cromosoma X. El estudio molecular se realiza por estudios indirectos por ser causada por mutaciones heterogéneas en ...
Yaixa Piloto Roque, Teresa Collazo Mesa, Manuel Gómez Martínez, Yadira Hernández Pérez, Yulemi Gónzalez Quesada, Ilienis Giraldo Rico, Lídice Reyes Navarro   +6 more
doaj  

Enzymatic Removal of Sialic Acid from Human Factor IX and Factor X Has No Effect on Their Coagulant Activity [PDF]

, 1995
Dwaipayan Bharadwaj, Reed J. Harris, Walter Kisiel, Kenneth J. Smith   +3 more
openalex   +1 more source

Virtual or In‐Person: Does It Matter? Comparing Pain, Function, Quality of Life, Self‐Efficacy, and Physical Function Outcomes of Virtual, Hybrid, and In‐Person Education and Exercise Program Participants

Arthritis Care &Research, EarlyView.
Objective This study aimed to determine if program format (in‐person, virtual, or hybrid) results in differences in 3‐month outcomes of pain, function, quality of life, self‐efficacy, and chair stands in a hip/knee osteoarthritis‐management program. Methods A secondary analysis of the Good Life with osteoArthritis in Denmark (GLA:D) Canada database was
Jill Van Damme, Vanina Dal Bello‐Haas, Ayse Kuspinar, Patricia Strachan, Michael Zywiel, James Young, Rhona McGlasson, Lisa C. Carlesso   +7 more
wiley   +1 more source

Hip morphology‐based osteoarthritis risk prediction models: development and external validation using individual participant data from the World COACH Consortium

Arthritis Care &Research, Accepted Article.
Objectives This study aims to develop hip morphology‐based radiographic hip osteoarthritis (RHOA) risk prediction models and investigates the added predictive value of hip morphology measurements and the generalizability to different populations. Methods We combined data from nine prospective cohort studies participating in the World COACH consortium ...
Myrthe A. van den Berg, Fleur Boel, Michiel M.A. van Buuren, Noortje S. Riedstra, Jinchi Tang, Harbeer Ahedi, Nigel K. Arden, Sita M.A. Bierma‐Zeinstra, Cindy G. Boer, Flavia M. Cicuttini, Timothy F. Cootes, David T. Felson, Willem Paul Gielis, Joshua Heerey, Graeme Jones, Stefan Kluzek, Nancy E. Lane, Claudia Lindner, Joyce B.J. van Meurs, Andrea Mosler, Amanda E. Nelson, Michael C. Nevitt, Edwin H. Oei, Jos Runhaar, Harrie Weinans, Jesse H. Krijthe, Rintje Agricola   +26 more
wiley   +1 more source