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Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response

Nature Network Boston, 2006
C. Manno   +31 more
semanticscholar   +1 more source

Immunologic studies of factor IX (christmas factor) I. Counterimmunoelectrophoresis method for factor IX antigen

Thrombosis Research, 1978
Abstract A precipitating monospecific antiserum for factor IX antigen was produced by immunization of rabbits with a partly purified factor IX and solid-phase immunoadsorption. The monospecific antiserum was used to determine the presence of factor IX antigen in hemophilia B and normal plasmas by a counterimmunoelectrophoresis method.
openaire   +3 more sources

Immunologic Studies of Factor IX (Christmas Factor)

British Journal of Haematology, 1978
A solid‐phase two‐site immunoradiometric assay has been developed which measures factor IX antigen levels as low as 0.0004 u per ml of plasma. In normal individuals, the factor IX antigen level correlated with the factor IX procoagulant level. In haemophilia B, 14 patients had markedly reduced antigen levels (<0.06 u/ml) and five had normal levels (&
openaire   +3 more sources

Standardization of assays of factor VIII and factor IX

La Ricerca in Clinica e in Laboratorio, 1990
The development of international standards over the last 15-20 years has led to improved interlaboratory agreement on assays of factor VIII and factor IX. In the most recent international collaborative study, the coefficient of variation for one-stage assays (26 laboratories) was 5.6%.
openaire   +3 more sources

Current treatment and recent progress in gastric cancer

Ca-A Cancer Journal for Clinicians, 2021
Smita S Joshi, Brian D Badgwell
exaly  

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