Results 51 to 60 of about 14,739,736 (367)

Metabolic, inflammatory and haemostatic effects of a low-dose continuous combined HRT in women with type 2 diabetes: potentially safer with respect to vascular risk? [PDF]

, 2003
BACKGROUND Conventional hormone replacement therapy (HRT) containing conjugated equine oestrogen (CEE) and medroxyprogesterone acetate (MPA) increases triglyceride, C- reactive protein (CRP) and coagulation Factor VII concentrations, potentially ...
Alan J. Jaap, Andersen, Anderson, Ann Rumley, Anne Kelly, Brussard, Cushman, Dichtl, Ferrara, Gordon D. Lowe, Gornstein, Herrington, Hokanson, Hulley, Ian A. Greer, John R. Petrie, Joyce McKenzie, Kanaya, Kenneth Paterson, Knopp, Koh, Kroon, Kroon, Lokkegaard, Lowe, Lowe, Lowe, Lynne Crawford, Manning, Meade, Naveed Sattar, Perera, Petitti, Pradhan, Rapp, Ridker, Ridker, Rossouw, Sattar, Sattar, Stephen Gallacher, Stork, Van Baal, Van Baal, Vehkavaara, Woodward, Zanger   +46 more
core   +1 more source

The role of fibroblast growth factors in cell and cancer metabolism

FEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

“Prevalence of Inhibitors in Hemophilia Patients and its Clinical Implications”: A Study of 276 Patients in Western India

Global Journal of Transfusion Medicine, 2019
Introduction: Hemophilia is an X-linked congenital bleeding disorder caused by a deficiency of coagulation factor VIII (FVIII) in hemophilia A (HA) or factor IX (FIX) in hemophilia B (HB).
Sangita Darshan Shah, Tarak R Patel, Nidhi M Bhatnagar, Maitrey D Gajjar, Mamta Chintan Shah, Sujata Tripathi   +5 more
doaj   +1 more source

The prognostic value of the hypoxia markers CA IX and GLUT 1 and the cytokines VEGF and IL 6 in head and neck squamous cell carcinoma treated by radiotherapy ± chemotherapy [PDF]

, 2005
BACKGROUND: Several parameters of the tumor microenvironment, such as hypoxia, inflammation and angiogenesis, play a critical role in tumor aggressiveness and treatment response.
A Dietz, CC Wykoff, DM Brizel, E Tartour, EP Hui, Erik Verbeken, H Mineta, Harlinde De Schutter, J Bussink, J Dunst, JA Forsythe, JH Kaanders, K Muraoka, Laurence Goethals, M Kunkel, M Nordsmark, MA St John, MI Koukourakis, P Mellanen, P Vaupel, R Airley, R Hermans, R Srivani, Robert Hermans, S Ivanov, S Pastorekova, Sandra Nuyts, T Tamatani, TN Teknos, V Brouazin-Jousseaume, V Michalaki, W Jelkmann, Willy Landuyt, Y Miyamoto, YC Chung, Z Chen   +35 more
core   +3 more sources

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Blood coagulation parameters in fallow deer (Dama dama)

Veterinární Medicína, 2011
There are frequent reports from around the world of wild animals being poisoned with anticoagulants. Granulated baits can result in primary or secondary poisoning of non-target animals.
Z. Siroka, B. Krocilova, J. Pikula, H. Bandouchova, L. Peckova, F. Vitula   +5 more
doaj   +1 more source

Efficacy of a high-purity factor IX concentrate in hemophilia B patients undergoing surgery [PDF]

Revista Brasileira de Hematologia e Hemoterapia, 2002
A plasma derived, high purity, solvent-detergent treated and subsequently nanofiltered factor IX concentrate (BEMOFIL) was evaluated in 19 hemophilia B patients, including four with severe, thirteen with mild or moderate type of disease and two ...
Vesa Rasi, Freja Ebeling
doaj   +1 more source

Scale-factor duality in string Bianchi cosmologies [PDF]

, 1999
We apply the scale factor duality transformations introduced in the context of the effective string theory to the anisotropic Bianchi-type models. We find dual models for all the Bianchi-types [except for types $VIII$ and $IX$] and construct for each of ...
Copeland E. J., ELISA DI PIETRO, Harvey A., JACQUES DEMARET   +3 more
core   +4 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Activation of Factor IX by Factor XIa - A Spectrophotometric Assay for Factor IX in Human Plasma [PDF]

Thrombosis and Haemostasis, 1982
SummaryThe activation of Factor IX by partially purified Factor XIa was followed by active site titration, gelelectrophoresis and by a spectrophotometric assay. The assay is based on the finding that the rate of Factor X activation in the presence of phospholipid and Ca2+ is linear in time and proportional to the amount of Factor IXa present and can be
Tans, G., Janssen-Claesssen, T., van Dieijen, G., Hemker, H.C., Rosing, J.   +4 more
openaire   +2 more sources