Results 61 to 70 of about 14,538,270 (379)

Pion Form Factor in the Light-Front

, 2004
The pion electromagnetic form factor is calculated with a light-front quark model. The "plus" and "minus" component of the electromagnetic current are used to calculate the electromagnetic form factor in the Breit frame with two models for the q\bar{q ...
de Melo, J. P. B. C.
core   +1 more source

The prognostic value of the hypoxia markers CA IX and GLUT 1 and the cytokines VEGF and IL 6 in head and neck squamous cell carcinoma treated by radiotherapy ± chemotherapy [PDF]

, 2005
BACKGROUND: Several parameters of the tumor microenvironment, such as hypoxia, inflammation and angiogenesis, play a critical role in tumor aggressiveness and treatment response.
A Dietz, CC Wykoff, DM Brizel, E Tartour, EP Hui, Erik Verbeken, H Mineta, Harlinde De Schutter, J Bussink, J Dunst, JA Forsythe, JH Kaanders, K Muraoka, Laurence Goethals, M Kunkel, M Nordsmark, MA St John, MI Koukourakis, P Mellanen, P Vaupel, R Airley, R Hermans, R Srivani, Robert Hermans, S Ivanov, S Pastorekova, Sandra Nuyts, T Tamatani, TN Teknos, V Brouazin-Jousseaume, V Michalaki, W Jelkmann, Willy Landuyt, Y Miyamoto, YC Chung, Z Chen   +35 more
core   +3 more sources

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

FEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan, Victoria Scarpelli, Marten Exterkate   +2 more
wiley   +1 more source

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

FEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura, Lixiang Wang, Nao Hasuzawa, Ayako Nagayama, Sawako Moriyama, Kenji Ashida, Yoshinori Moriyama, Masatoshi Nomura, Ken Yamamoto   +8 more
wiley   +1 more source

Clinical profile and demographic characteristics of moderate and severe hemophilia patients in a tertiary care hospital of Bangladesh

Orphanet Journal of Rare Diseases, 2022
Background Hemophilia is one of the commonest inherited bleeding disorders which may lead to chronic bleeding tendencies and life-long disabilities if not properly managed.
Mohammed Nadimul Islam, Akhil Ranjon Biswas, Humayra Nazneen, Nobendu Chowdhury, Mahbubul Alam, Jayanta Banik, Md. Kamrul Hassan, Abdullah Az Zubayer Khan, Najmul Karim, Mohammad Jahid Hasan, Md. Abdullah Saeed Khan   +10 more
doaj   +1 more source

The Coronal X-ray Spectrum of the Multiple Weak-Lined T Tauri Star System HD 98800 [PDF]

, 2004
We present high-resolution X-ray spectra of the multiple (hierarchical quadruple) weak-lined T Tauri star system HD 98800, obtained with the High Energy Transmission Gratings Spectrograph (HETGS) aboard the Chandra X-ray Observatory (CXO).
Claude R. Canizares, David A. Weintraub, David P. Huenemoerder, Favata F., Jingqiang Li, Joel H. Kastner, Norbert S. Schulz, Sylvester R. J.   +7 more
core   +3 more sources

Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1

FEBS Letters, EarlyView.
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri, Andrea Lapucci, Giuseppe Orsomando, Nadia Raffaelli, Alberto Chiarugi, Daniela Buonvicino   +5 more
wiley   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Signaling mechanisms of the platelet glycoprotein Ib-IX complex

Platelets, 2022
The glycoprotein Ib–IX (GPIb-IX) complex mediates initial platelet adhesion to von Willebrand factor (VWF) immobilized on subendothelial matrix and endothelial surfaces, and transmits VWF binding-induced signals to stimulate platelet activation.
Yaping Zhang, Samuel M Ehrlich, Cheng Zhu, Xiaoping Du   +3 more
doaj   +1 more source

Treatment of hemophilia B: focus on recombinant factor IX

Biologics : targets & therapy, 2013
Hemophilia B is a recessive X-linked bleeding disorder characterized by deficiency of the coagulation factor IX (FIX). In hemophilia B patients the severity of the bleeding phenotype is related to the degree of the FIX defect.
M. Franchini, F. Frattini, S. Crestani, C. Sissa, C. Bonfanti   +4 more
semanticscholar   +1 more source