The A2 Subunit of Factor VIIIa Modulates the Active Site of Factor IXa [PDF]
Factor VIIIa, the protein cofactor for factor IXa, is comprised of A1, A2, and A3-C1-C2 subunits. Isolated subunits of factor VIIIa were examined for their ability to accelerate the factor IXa-catalyzed activation of factor X. The A2 subunit enhanced the kcat for this conversion by 100-fold whereas the Km for factor X was unaffected.
Philip J. Fay, Kyoko Koshibu
openaire +3 more sources
Leggett-Garg macrorealism and the quantum nondisturbance conditions
We investigate the relation between a refined version of Leggett and Garg conditions for macrorealism, namely the no-signaling-in-time (NSIT) conditions, and the quantum mechanical notion of nondisturbance between measurements.
Budroni, Costantino+2 more
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Modeling Task Effects in Human Reading with Neural Attention [PDF]
Humans read by making a sequence of fixations and saccades. They often skip words, without apparent detriment to understanding. We offer a novel explanation for skipping: readers optimize a tradeoff between performing a language-related task and fixating
Hahn, Michael, Keller, Frank
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Stabilization of thrombin-activated porcine factor VIII:C by factor IXa phospholipid [PDF]
Abstract The activation of porcine factor X by an enzymatic complex consisting of activated factor IX (factor IXa), thrombin-activated factor VIII:C (factor VIII:Ca), phospholipid vesicles, and calcium was studied in the presence of an irreversible inhibitor of factor Xa, 5-dimethylamino- naphthalene-1-sulfonyl-glutamyl-glycyl-arginyl ...
Gaylord J. Knutson+2 more
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Black anglerfish (Lophius budegassa): weight-length relationships, weight conversion factors and condition factor trends from a decade of two stocks, in ICES Div. VIIIc-IXa (northern Iberian Atlantic waters) and in Div. VIIb,c,h,j,k (Celtic Sea, south-western Ireland and Porcupine Bank) [PDF]
Weight-length relationships, weight conversion factors and condition factor are presented from a decade (2006 to 2015) for both stocks of black anglerfish (Lophius budegassa) in northern Iberian Atlantic waters (ICES Div.
Antolínez, A. (Ana)+3 more
core
Two-Point Functions of Coulomb Gauge Yang-Mills Theory
The functional approach to Coulomb gauge Yang-Mills theory is considered within the standard, second order, formalism. The Dyson-Schwinger equations and Slavnov-Taylor identities concerning the two-point functions are derived explicitly and one-loop ...
A. Cucchieri+5 more
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Frequency-domain gravitational waves from non-precessing black-hole binaries. II. A phenomenological model for the advanced detector era [PDF]
We present a new frequency-domain phenomenological model of the gravitational-wave signal from the inspiral, merger and ringdown of non-precessing (aligned-spin) black-hole binaries.
Bohé, Alejandro+6 more
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Black hole uniqueness theorems and new thermodynamic identities in eleven dimensional supergravity
We consider stationary, non-extremal black holes in 11-dimensional supergravity having isometry group $\mathbb{R} \times U(1)^8$. We prove that such a black hole is uniquely specified by its angular momenta, its electric charges associated with the ...
Bossard G+28 more
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A novel factor IXa–specific enzyme-linked immunosorbent assay detects factor IXa in human plasma
Factor (F)IXa activity has been detected in human plasma and may impact thrombotic risk. Current FIXa activity assays are complex and cumbersome.To develop a reproducible enzyme-linked immunosorbent assay (ELISA) using a novel monoclonal antibody that detects total FIXa in human plasma.A monoclonal antibody was raised against the new N-terminus exposed
Misenheimer, Tina M.+4 more
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Effective Lagrangian and Topological Interactions in Supersolids
We construct a low-energy effective Lagrangian describing zero-temperature supersolids. Galilean invariance imposes strict constraints on the form of the effective Lagrangian.
A. F. Andreev, D. T. Son, H. Leutwyler
core +1 more source