Results 81 to 90 of about 12,216,288 (253)

The Effects of Spermine and Spermidine on the Interactions of Human Factors IXa, Xa, XIa, and IIa wi [PDF]

open access: yes, 2013
Heparin is a common anticoagulant used in hospitals that has been found to promote the interaction of human factor IXa with Anti-Thrombin III, creating a [IXa-ATIII] complex when put through electrophoresis.
Menicucci, Caitlyn
core   +1 more source

The Effect of Postoperative Antithrombin Supplementation on the Inflammatory and Coagulation Status of a Surgically Treated Patient With a Malignant Tumor in the Small Pelvis—Case Series

open access: yesCancer Reports, Volume 8, Issue 6, June 2025.
ABSTRACT Introduction Antithrombin has the function of a natural anticoagulant. It is the main component of the inhibitory anticoagulant system, which, under physiological conditions, opposes the procoagulant mechanisms of hemostasis, preventing the occurrence of a hypercoagulable state, the development of thrombosis, and thromboembolic complications ...
Ranko Lazović, Ognjenka Šarenac
wiley   +1 more source

Inhibition of factor IXa by the pegnivacogin system during cardiopulmonary bypass: a potential substitute for heparin. A study in baboons.

open access: yesEuropean Journal of Cardio-Thoracic Surgery, 2016
OBJECTIVES Heparin and protamine are standard for anticoagulation and reversal for cardiopulmonary bypass (CPB). The REGADO biosciences protocol 1 (REG1) anticoagulant system, consisting of the Factor IXa (FIXa)-inhibitor pegnivacogin and its reversal ...
A. Bel   +11 more
semanticscholar   +1 more source

Comparative interactions of factor IX and factor IXa with human platelets

open access: yesJournal of Biological Chemistry, 1989
Both factor IX and factor IXa were bound to gel filtered platelets in the presence of CaCl2 (2-20 mM) and human alpha-thrombin (0.06-0.2 units/ml) with maximal binding occurring in 10-20 min at 37 degrees C, and rapid reversibility was observed when unlabeled ligands were added in 100-fold molar excess.
Peter N. Walsh   +2 more
openaire   +3 more sources

The Kinematic Algebras from the Scattering Equations [PDF]

open access: yes, 2013
We study kinematic algebras associated to the recently proposed scattering equations, which arise in the description of the scattering of massless particles.
Monteiro, Ricardo, O'Connell, Donal
core   +2 more sources

Critical current and stability effects between 0 and 6 tesla in mono and multifilamentary NbTi conductors having a CuNi matrix [PDF]

open access: yes, 1985
We investigated the current carrying capacities of ten NbTi superconductors having a CuNi matrix with diameters between 50 and 300 ¿m as function of an applied magnetic field of 0 to 6 tesla.
Kate, H.H.J. ten   +2 more
core   +3 more sources

Systems biology of coagulation initiation: kinetics of thrombin generation in resting and activated human blood.

open access: yesPLoS Computational Biology, 2010
Blood function defines bleeding and clotting risks and dictates approaches for clinical intervention. Independent of adding exogenous tissue factor (TF), human blood treated in vitro with corn trypsin inhibitor (CTI, to block Factor XIIa) will generate ...
Manash S Chatterjee   +3 more
doaj   +1 more source

A Single‐Center Study on Frontline Treatment for Multiple Myeloma Patients With 1q Abnormalities

open access: yeseJHaem, Volume 6, Issue 3, June 2025.
ABSTRACT Introduction Chromosome 1q copy gains (with‐1q‐gain) is a frequently observed genetic abnormality in multiple myeloma (MM) patients. Recent research has demonstrated that 1q gain is a prognostic factor, linked to poorer clinical outcomes. Methods This study was conducted at the Princess Margaret Cancer Centre to examine the clinical outcomes ...
Ashish Patel   +13 more
wiley   +1 more source

On Non-linear Action for Gauged M2-brane [PDF]

open access: yes, 2009
We propose a non-linear extension of U(1) \times U(1) (abelian) ABJM model including T_{M2} (higher derivative) corrections. The action proposed here is expected to describe a single M2-brane proving C^4/Z_k target space.
A Gustavsson   +40 more
core   +1 more source

The Gla Domain of Factor IXa Binds to Factor VIIIa in the Tenase Complex [PDF]

open access: yesJournal of Biological Chemistry, 2003
During blood coagulation factor IXa binds to factor VIIIa on phospholipid membranes to form an enzymatic complex, the tenase complex. To test whether there is a protein-protein contact site between the gamma-carboxyglutamic acid (Gla) domain of factor IXa and factor VIIIa, we demonstrated that an antibody to the Gla domain of factor IXa inhibited ...
Blostein, Mark D.   +3 more
openaire   +4 more sources

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