Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Psychometric properties and factor structure of the Children's Eating Behavior Questionnaire in a Danish sample of children with overweight and obesity. [PDF]
Pauls DD, Abild CB, Clausen L, Bruun JM.
europepmc +1 more source
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Dataset on the exploratory factor structure of organizational health performance for micro and small enterprises: The initial research stage. [PDF]
Sunarsih U +6 more
europepmc +1 more source
Organizational mobilization, action strategy and opportunity structure: Factors affecting the results of homeowners’ collective actions [PDF]
Zhiming Sheng
openalex +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Psychometric properties and factor structure of the short form of the cyberchondria severity scale (CSS-12) amongst Indian adults. [PDF]
Dharshini R +3 more
europepmc +1 more source
BFCS: Bayes Factors of Covariance Structures
Ioan Gabriel Bucur +2 more
openalex +2 more sources
The crystal structure of the RsbN–σBldN complex from Streptomyces venezuelae defines a new structural class of anti-σ factor [PDF]
Maria A. Schumacher +6 more
openalex +1 more source

