Activity of Labile Coagulation Factors, Factor X and Fibrinogen Level in Frozen Plasma versus Fresh Frozen Plasma [PDF]
Journal of Clinical and Diagnostic Research, 2023 Introduction: Fresh Frozen Plasma (FFP) is a blood component separated from whole blood and frozen below -30°C within 8 hours of donation for optimum preservation of coagulation factors. However, logistic and geographical reasons may hamper separation of
Swarupa Nikhil Bhagwat +3 more
doaj +1 more source
Association of prothrombin, FV Leiden and MTHFR gene polymorphisms in the Montenegrin patients with venous thromboembolism [PDF]
Vojnosanitetski Pregled, 2021 Background/Aim. Polymorphisms of the factor V Leiden (FV G1691A), prothrombin (FII G20210A), and methylene-tetrahydrofolate reductase (MTHFR C677T) genes are the most commonly investigated inherited risk factors for developing venous thromboembolism (VTE)
Teofilov Slađana +4 more
doaj +1 more source
Novel single nucleotide mutations in exon-10 of human coagulation Factor V gene in patients with pulmonary thromboembolism [PDF]
Journal of Cardiovascular and Thoracic Research, 2020 Introduction: Acute pulmonary thromboembolism (PTE) presents with wide spectrum and has variable prognosis. Factor V Leiden (FVL) is the most common inherited thrombophilia, with a prevalence of 3%-7% in the general US population, approximately 5% in ...
Latheef Kasala +2 more
doaj +1 more source
Association of Factor II G20210A, Factor V G1691A and methylenetetrahydrofolate reductase C677T gene polymorphism with different forms of myocardial infarction: ST segment elevation and non-ST segment elevation [PDF]
Vojnosanitetski Pregled, 2020 Background/Aim. Coagulation Factor II G20210A and Factor V G1691A variants are moderately associated with coronary artery disease. Polymorphism of methylenetetrahydrofolate reductase (MTHFR) gene C677T is associated with myocardial infarction (MI) in ...
Ćućuz-Jokić Milica +4 more
doaj +1 more source
Analysis of f5 gene polymorphism in men with coronary atherosclerosis using whole exome sequencing
Атеросклероз, 2021 Factor V, encoded by the F5 gene, is a procoagulant blood clotting factor that increases the production of thrombin, the central enzyme that converts fibrinogen to fibrin, which leads to the formation of a blood clot.
E. V. Striukova +11 more
doaj +1 more source
Seminars in Thrombosis and Hemostasis, 2009 Congenital factor V (FV) deficiency is a bleeding disorder associated with mild to severe hemorrhagic symptoms and a prevalence in the general population of 1 in 1,000,000 in the homozygous form. Patients with FV deficiency and clinically significant manifestations (mainly involving mucosal tracts) show very low or unmeasurable plasma FV levels and are
R. Asselta, F. Peyvandi
openaire +2 more sources
Frontiers in Pediatrics, 2022 We summarized two cases of congenital factor V deficiency (FVD) associated with a novel F5 mutation, and analyzed the relationship of the clinical features and genetic characteristics in congenital FVD.
Lin Cheng, Ying Li, Wenjuan Zhou, Tao Bo
doaj +1 more source
A Case of Acquired Factor V Deficiency in Patient with Bleeding
TH Open, 2020 Low frequency of rare diseases origins from missed diagnosis addressing to poor prognosis. Acquired factor V inhibitor is a very low frequent bleeding condition (prevalence: 0.09/100,000,000–0.29/1,000,000 per year).
Davide Vetri +6 more
doaj +1 more source
Frontiers in Medicine, 2022 BackgroundFactor V (FV) deficiency is a rare disease, with a low incidence rate in Asia. Therefore, the F5 mutation in the Taiwanese population is poorly understood.MethodsA Chinese family with FV deficiency was included, and the patient and his family ...
Yueh-Shih Chang +8 more
doaj +1 more source
Coagulation factor V is a marker of tumor-infiltrating immune cells in breast cancer
OncoImmunology, 2020 Background Factor (F) V is an essential cofactor in blood coagulation, however, F5 expression in breast tumors has also been linked to tumor aggressiveness and overall survival. The specific role of FV in breast cancer is yet unknown.
Mari Tinholt +8 more
doaj +1 more source