Results 11 to 20 of about 2,341,716 (244)
Association of factor V deficiency with factor V HR2
Haematologica, 2004 BACKGROUND AND OBJECTIVES: Factor V HR2 possesses decreased co-factor activity to activated protein C and an increased ratio of factor V1 to factor V2. Factor V HR2 is associated with a mild increase in the risk of venous thromboembolism although not all
EM Faioni +4 more
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Seminars in Thrombosis and Hemostasis, 2009 Congenital factor V (FV) deficiency is a bleeding disorder associated with mild to severe hemorrhagic symptoms and a prevalence in the general population of 1 in 1,000,000 in the homozygous form. Patients with FV deficiency and clinically significant manifestations (mainly involving mucosal tracts) show very low or unmeasurable plasma FV levels and are
R. Asselta, F. Peyvandi
openaire +2 more sources
Coagulation factor V is a marker of tumor-infiltrating immune cells in breast cancer
OncoImmunology, 2020 Background Factor (F) V is an essential cofactor in blood coagulation, however, F5 expression in breast tumors has also been linked to tumor aggressiveness and overall survival. The specific role of FV in breast cancer is yet unknown.
Mari Tinholt +8 more
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Frontiers in Medicine, 2022 BackgroundFactor V (FV) deficiency is a rare disease, with a low incidence rate in Asia. Therefore, the F5 mutation in the Taiwanese population is poorly understood.MethodsA Chinese family with FV deficiency was included, and the patient and his family ...
Yueh-Shih Chang +8 more
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Comparison between thrombophilic gene polymorphisms among high risk patients
Romanian Journal of Internal Medicine, 2020 Introduction. The purpose of this study was to compare the role of the thrombophilic variants among two groups of high risk patients with vascular disorders and recurrent pregnancy loss.
Levkova Mariya +4 more
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مجله دانشگاه علوم پزشکی گرگان, 2023 Background and Objective: Gene mutations leading to thrombophilic disorders and changes in blood coagulation factors during pregnancy play an important role in the occurrence of recurrent abortions.
Masoomeh Rezanezhadi +1 more
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Pakistan Armed Forces Medical Journal, 2022 Objective: To determine the diagnostic accuracy of clotting based APCR assay in determining Factor V Leiden mutation with PCR as gold standard and to establish the frequency of factor V Leiden mutation in patients presenting with thrombophilia as well ...
Sidra Barlas +5 more
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The Factor V Activation Paradox [PDF]
Journal of Biological Chemistry, 2004 The prothrombinase complex consists of the protease factor Xa, Ca2+, and factor Va assembled on an anionic membrane. Factor Va functions both as a receptor for factor Xa and a positive effector of factor Xa catalytic efficiency and thus is key to efficient conversion of prothrombin to thrombin.
Thomas, Orfeo +5 more
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Memorias do Instituto Oswaldo Cruz, 2019 BACKGROUND Despite a highly efficacious vaccine, yellow fever (YF) is still a major threat in developing countries and a cause of outbreaks. In 2018, the Brazilian state of São Paulo witnessed a new YF outbreak in areas where the virus has not been ...
Luciana Vilas Boas Casadio +11 more
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Multiple Coagulation Factor Deficiency: A Series of Eight Cases [PDF]
Journal of Clinical and Diagnostic ResearchMultiple Coagulation Factor Deficiency (MCFD) is an uncommon haematological disorder characterised by simultaneous deficiency of multiple clotting factors, which leads to an increased risk of bleeding and compromised haemostasis. The present series aimed
Abhijith Lakshman +2 more
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