Results 11 to 20 of about 2,320,405 (244)
We summarized two cases of congenital factor V deficiency (FVD) associated with a novel F5 mutation, and analyzed the relationship of the clinical features and genetic characteristics in congenital FVD.
Lin Cheng, Ying Li, Wenjuan Zhou, Tao Bo
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Coagulation factor V is a marker of tumor-infiltrating immune cells in breast cancer
Background Factor (F) V is an essential cofactor in blood coagulation, however, F5 expression in breast tumors has also been linked to tumor aggressiveness and overall survival. The specific role of FV in breast cancer is yet unknown.
Mari Tinholt +8 more
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BackgroundFactor V (FV) deficiency is a rare disease, with a low incidence rate in Asia. Therefore, the F5 mutation in the Taiwanese population is poorly understood.MethodsA Chinese family with FV deficiency was included, and the patient and his family ...
Yueh-Shih Chang +8 more
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Comparison between thrombophilic gene polymorphisms among high risk patients
Introduction. The purpose of this study was to compare the role of the thrombophilic variants among two groups of high risk patients with vascular disorders and recurrent pregnancy loss.
Levkova Mariya +4 more
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Background and Objective: Gene mutations leading to thrombophilic disorders and changes in blood coagulation factors during pregnancy play an important role in the occurrence of recurrent abortions.
Masoomeh Rezanezhadi +1 more
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Objective: To determine the diagnostic accuracy of clotting based APCR assay in determining Factor V Leiden mutation with PCR as gold standard and to establish the frequency of factor V Leiden mutation in patients presenting with thrombophilia as well ...
Sidra Barlas +5 more
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BACKGROUND Despite a highly efficacious vaccine, yellow fever (YF) is still a major threat in developing countries and a cause of outbreaks. In 2018, the Brazilian state of São Paulo witnessed a new YF outbreak in areas where the virus has not been ...
Luciana Vilas Boas Casadio +11 more
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The Factor V Activation Paradox [PDF]
The prothrombinase complex consists of the protease factor Xa, Ca2+, and factor Va assembled on an anionic membrane. Factor Va functions both as a receptor for factor Xa and a positive effector of factor Xa catalytic efficiency and thus is key to efficient conversion of prothrombin to thrombin.
Thomas, Orfeo +5 more
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Multiple Coagulation Factor Deficiency: A Series of Eight Cases [PDF]
Multiple Coagulation Factor Deficiency (MCFD) is an uncommon haematological disorder characterised by simultaneous deficiency of multiple clotting factors, which leads to an increased risk of bleeding and compromised haemostasis. The present series aimed
Abhijith Lakshman +2 more
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Factores asociados a la violencia de género en mujeres del Centro Poblado de La Esperanza, Huánuco
Objective. To describe the factors that are associated with gender-based violence. Methods. An observational, transversal, prospective and correlational research was carried out on a sample of 333 women from the esperanza populated centre, amarilis ...
Amalia Leiva Yaro
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