Results 261 to 270 of about 2,453,026 (292)
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Factor V inhibitor in thrombosis
American Journal of Hematology, 1993AbstractA 68‐year‐old previously well woman developed sudden onset of limb gangrene in association with liver dysfunction. An immediately acting inhibitor to factor V with some of the features of lupus anticoagulant was demonstrated. The patient required limb amputation within 2 weeks and activity of the anticoagulant seemed to be on the decline 6 ...
A, Kapur, P R, Kelsey, P E, Isaacs
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Observations on a Factor‐V Inhibitor
British Journal of Haematology, 1975Summary. A 67‐year‐old man developed a potent inhibitor of factor V shortly after undergoing blood transfusions and surgery. The inhibitor reacted in a time‐dependent manner with factor V and gave a non‐linear concentration graph. Studies with specific antisera indicated that it contained γ and μ heavy chains and both κ and λ light chains.
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Thrombosis and Haemostasis, 2013
SummaryFactor V Leiden is a procoagulant mutation associated with venous and arterial thrombosis and pregnancy complications. Its high prevalence of 5% in Caucasians suggests that there are evolutionary benefits as well. Carriers are indeed reported to have various advantageous phenotypes related to haemostasis, inflammation and fertility: less acute ...
Thijs E, van Mens +2 more
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SummaryFactor V Leiden is a procoagulant mutation associated with venous and arterial thrombosis and pregnancy complications. Its high prevalence of 5% in Caucasians suggests that there are evolutionary benefits as well. Carriers are indeed reported to have various advantageous phenotypes related to haemostasis, inflammation and fertility: less acute ...
Thijs E, van Mens +2 more
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Platelet factor V to the rescue
Blood, 2010In this issue of Blood, Duckers and colleagues show that residual platelet factor V is sufficient to promote thrombin generation and likely protects against major bleeding in patients with undetectable plasma factor V.
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Factor V Leiden and Contraception
Journal of Midwifery & Women's Health, 2004Factor V Leiden is the most common genetic cause of primary and recurrent venous thromboembolism in women. It is an inherited thrombophilia that results from a genetic mutation. A college‐aged woman who presented for care and had a positive family history of venous thrombosis tested positive for Factor V Leiden.
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Nature, 1964
COAGULATION factor V is involved in the production of both extrinsic and intrinsic thromboplastin in the blood. It deteriorates rapidly during blood storage and the one-stage prothrombin time of stored plasma is prolonged because of factor V deficiency. The factor V concentration of test material may be determined by adding dilutions to aged plasma and
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COAGULATION factor V is involved in the production of both extrinsic and intrinsic thromboplastin in the blood. It deteriorates rapidly during blood storage and the one-stage prothrombin time of stored plasma is prolonged because of factor V deficiency. The factor V concentration of test material may be determined by adding dilutions to aged plasma and
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Studies on factor V in animals
Journal of Comparative Pathology, 1967Summary Studies have been made on the effect of storage and temperature on factor V in animals and a method for its assay is described. There was a decrease of the factor with age in oxalated plasma of cattle, horses, sheep, dogs, rabbits and one elephant. This deterioration was very rapid in plasma kept at 37C.
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