Results 201 to 210 of about 964,911 (327)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

A child with factor V deficiency with a novel F5 gene mutation misdiagnosed as a left iliac fossa abscess: A case report. [PDF]

Medicine (Baltimore)
Zhang Y, Liu L, Guo Q, Li Y, Luo S, Wan C, Zhu Y.   +6 more
europepmc   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Characterization of zebrafish coagulation cofactors Fviii and Fv mutants and modeling hemophilia A and factor V deficiency. [PDF]

Blood Coagul Fibrinolysis
Dhinoja S, De Maria A, Qaryoute AA, Jagadeeswaran P.   +3 more
europepmc   +1 more source

Successful Management of Life-threatening Pelvic Hemorrhage From Acquired Factor V Deficiency With immunosuppressive Therapy. [PDF]

Cureus, 2020
Wu AH, Manje Gowda A, Peng S, Kaur S, Maroules M.   +4 more
europepmc   +1 more source

Combined Congenital Deficiency of Factor V and Factor VIII [PDF]

Acta Haematologica, 1982
D, Mazzone, A, Fichera, G, Praticò, F, Sciacca   +3 more
openaire   +2 more sources

Heterozygous large deletion mimicking homozygous substitution in MCFD2 in a patient with combined Factor V and Factor VIII deficiency [PDF]

Hamdi Rezigue, Pierre Chamouni, Mathilde Frétigny, Virginie Barbay, Véronique Le Cam‐Duchez, Victor Bobée, Simon Lanne, C. Dumesnil, Christine Vinciguerra, Pascale Schneider, Yohann Jourdy   +10 more
openalex   +1 more source

Population differences in the frequency of the factor V Leiden variant among people with clinically symptomatic protein C deficiency. [PDF]

, 1995
P Hallam, DS Millar, Michael Krawczak, V V Kakkar, D.N. Cooper   +4 more
openalex   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

A First Case Report of Autoimmune Acquired Factor V Deficiency After Severe Acute Respiratory Syndrome Coronavirus 2 mRNA Vaccination at the Time of Initiating Haemodialysis. [PDF]

Nephrology (Carlton)
Tasaki A, Fukuda A, Kudo A, Nishikawa E, Koumatsu N, Wada M, Okita J, Maruo M, Uchida H, Nakata T, Itani K, Shibata H.   +11 more
europepmc   +1 more source