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Factor V Deficiency: A Subtle Presentation
The Indian Journal of Pediatrics, 2013Congenital factor V deficiency (also known as labile factor or proaccelerin) is a rather uncommon [1:1000,000] inherited coagulopathy (autosomal recessive inheritance). Affected patients become symptomatic in early childhood with spontaneous or post-traumatic bleeding complications.
Mukesh Uttamchand, Sanklecha +2 more
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A Comprehensive Overview of Coagulation Factor V and Congenital Factor V Deficiency
Seminars in Thrombosis and Hemostasis, 2019AbstractCoagulation factor (F) V is a glycoprotein that plays an essential role in the formation of the prothrombinase complex, which is critical for progressing clot formation. FV deficiency is a rare bleeding disorder with an estimated incidence of one per 1 million in the general population.
Shadi, Tabibian +8 more
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Factor V and Combined Factor V and VIII Deficiency
2018This chapter outlines the pathophysiology, clinical presentation, inheritance and incidence of factor V deficiency and combined factors V and VIII deficiency. The chapter describes the interaction with pregnancy and discusses the medical and anesthetic management of pregnant women with factor V deficiency or combined factors V and VIII deficiency.
James P. R. Brown, Joanne Douglas
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A description of two cases of factor V deficiency
Haemophilia, 1995Summary We report two cases of factor V deficiency. A 12‐year‐old girl with thalassemia major was admitted for bone marrow transplant (mismatched). She was found to have a heterozygous deficiency of factor V (21%), but this was considered compatible with the transplant, which was performed without the support of suppernatant cryoprecipitate.
F, Cerneca +4 more
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Factor V Deficiency and Thrombocytopenia in a Dog with Adenocarcinoma
Journal of the American Veterinary Medical Association, 1972SUMMARY A 9-year-old spayed female Beagle was found to have thrombocytopenia, coagulation-factor V deficiency, and adenocarcinoma originating from nasal epithelium. The deficiency of factors concerned with normal hemostasia was believed to be associated with chronic intravascular coagulation similar to the consumption coagulopathy syndrome of man.
K W, Prasse +3 more
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Intracranial haemorrhage due to factor V deficiency
Acta Paediatrica, 1999Factor V deficiency is a rare coagulation disorder which is inherited autosomal recessively. Factor V deficiency should be considered in infants with bleeding disorders and prolonged prothrombin and activated partial thromboplastin times if bleeding continues in spite of vitamin K injection.
Totan, M, Albayrak, D
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Gastric Bypass in a Factor V Deficient Patient
Obesity Surgery, 2006Factor V deficiency is a rare bleeding disorder requiring special attention during the peri-operative period. Surgical intervention in these patients can be technically challenging. Because of the rarity of this condition, the optimal management is unknown. Available literature supports peri-operative infusion of fresh frozen plasma.
Syed, Husain +2 more
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Inherited factor V deficient neonate with galactosaemia
Clinical Biochemistry, 2011Reporting a case of inherited factor V deficiency and galactosemia.A neonate was admitted with hematoma, jaundice, splenomegaly, diarrhea, anemia, abdominal ascites and bilateral cataracts that diagnosis of galactosaemia and factor V deficiency was established.Coinheritance of both coagulation disorder and metabolic disorder is very rare episode that ...
Hassan, Mansouritorghabeh +2 more
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Parahemophilia: New Insights into Factor V Deficiency
Seminars in Thrombosis and Hemostasis, 2013Blood coagulation factor V (FV) plays a pivotal role in blood coagulation. It is found in both plasma and in platelets and has a profound impact on thrombin generation. Deficiency of this clotting factor due to inherited or acquired conditions results in a broad spectrum of bleeding symptoms. Surprisingly however, some patients with undetectable levels
Nabil, Thalji, Rodney M, Camire
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Factor V deficiency and pregnancy: a case report
Annales de biologie clinique, 2011The factor V deficiency is a very rare hereditary disease of the coagulation, which is accompanied by a high hemorrhagic risk in the event of delivery and in the post-partum. We report the case of a woman having a factor V deficiency which had a pregnancy, and which gave birth by Cesarean, as replacement therapy we proposed the transfusion of 20 mL/kg ...
Mohamed, Ayedi +7 more
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