Results 211 to 220 of about 964,911 (327)

Familial intracranial haemorrhage due to factor V deficiency. [PDF]

, 1992
R S Wadia, Shashi Sangle, S Kripalaney, M Bafna, SJ Karve   +4 more
openalex   +1 more source

Case report on perioperative management of combined factor V and VIII deficiency in a patient with prolapse uterus

, 2023
Bhavani Sree K. P., Usha Rani G.
openalex   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

[Clinical and genetic analyses of hereditary factor Ⅴ deficiency cases]. [PDF]

Zhonghua Xue Ye Xue Za Zhi, 2021
Zhang DL, Xue F, Dou XQ, Liu XF, Fu RF, Chen YF, Liu W, Jia YJ, Wang YH, Xiao ZJ, Zhang L, Yang RC.   +11 more
europepmc   +1 more source

Perioperative replacement therapy for a patient with hereditary factor V deficiency.

, 1990
Shinya Ueno, Yasuhiro Umeki, Hiroko Tsuda, Shosuke Takahashi, Junichi Yoshitake   +4 more
openalex   +2 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Congenital factor V deficiency from compound heterozygous mutations with a novel variant c.2426del (p.Pro809Hisfs*2) in the F5 gene: A case report. [PDF]

Medicine (Baltimore), 2020
Park CH, Park MS, Lee KO, Kim SH, Park YS, Kim HJ.   +5 more
europepmc   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Evaluation of Thrombophilia Profile in Northern Pakistan: Frequency and Presentation

Journal of Islamic International Medical College
Objective: This study aims to ascertain the prevalence of thrombotic disorders and thrombophilia profile among patients in Northern Pakistan. Study Design: Cross sectional descriptive study.
Omama Abbasi, Ayesha Junaid.
doaj