Perinatal Gene Transfer to the Liver [PDF]
, 2011 The liver acts as a host to many functions hence raising the possibility that any one may be compromised by a single gene defect. Inherited or de novo mutations in these genes may result in relatively mild diseases or be so devastating that death within
Buckley, SM +6 more
core +1 more source
Successful coronary stenting in a patient with factor V deficiency in the absence of fresh frozen plasma transfusion: Case report. [PDF]
Medicine (Baltimore), 2017 Choi S, Song M.
europepmc +2 more sources
CONGENITAL FACTOR V DEFICIENCY: CASE REPORTS
Russian journal of hematology and transfusiology, 2019 Introduction. Haemophilia and von Willebrand disease constitute the most common hereditary coagulopathies. However, such rare hereditary coagulopathies as congenital factor V defi ciency can mistakingly be referred to these diseases.Aim.
E. Yakovleva +8 more
semanticscholar +1 more source
Bone matrix components activate the NLRP3 inflammasome and promote osteoclast differentiation [PDF]
, 2017 The NLRP3 inflammasome senses a variety of signals referred to as danger associated molecular patterns (DAMPs), including those triggered by crystalline particulates or degradation products of extracellular matrix. Since some DAMPs confer tissue-specific
Abu-Amer, Yousef +9 more
core +2 more sources
Blood Coagulation and Fibrinolysis, 2016 &NA; Acquired factor V deficiency (AFVD) is a rare haemostatic disorder that is primarily because of the development of factor V inhibitors. Approximately, 200 cases have been reported and the greatest portion of these cases was because of bovine ...
Xiangyu Wang +7 more
semanticscholar +1 more source
The HI content of the Eridanus group of galaxies [PDF]
, 2004 The HI content of galaxies in the Eridanus group is studied using the GMRT observations and the HIPASS data. A significant HI deficiency up to a factor of 2-3 is observed in galaxies in the high galaxy density regions.
A. Biviano +31 more
core +3 more sources
Deficiency of G1 regulators P53, P21Cip1 and/or pRb decreases hepatocyte sensitivity to TGFbeta cell cycle arrest [PDF]
, 2015 TGFbeta is critical to control hepatocyte proliferation by inducing G1-growth arrest through multiple pathways leading to inhibition of E2F transcription activity.
Bellamy, Christopher O +4 more
core +1 more source
A case of congenital factor V deficiency [PDF]
Journal of Korean Medical Science, 1987 A case of Factor V deficiency, the first case in Korea, is reported in a 9-year-old boy whose plasma concentration of Factor V was 6%. He complained of easy bruisability, prolonged bleeding from the mouth after minor trauma and hemarthrosis and flexion contracture of the right knee.
J W, Song, M R, Um, H S, Ahn, C Y, Hong
openaire +2 more sources
Aortic Valve Replacement in Severe Factor V Deficiency and Inhibitor: Diagnostic and Management Challenges. [PDF]
Cureus, 2019 Bello A, Salazar E, Heyne K, Varon J.
europepmc +3 more sources
Loss of ATF3 exacerbates liver damage through the activation of mTOR/p70S6K/ HIF-1α signaling pathway in liver inflammatory injury. [PDF]
, 2018 Activating transcription factor 3 (ATF3) is a stress-induced transcription factor that plays important roles in regulating immune and metabolic homeostasis.
Jiang, Bin +9 more
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