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World distribution of factor V Leiden
The Lancet, 1995We have analysed 3380 chromosomes (1690 unrelated individuals) from twenty-four populations for the presence of factor V Leiden, an important risk factor in venous thromboembolism. The allele frequency in 618 Europeans was 4.4%, with the highest prevalence among Greeks (7%). It was 0.6% in Asia Minor.
D C, Rees, M, Cox, J B, Clegg
semanticscholar +5 more sources
JAMA
This JAMA Insights explores factor V Leiden, an inherited thrombophilia, and its association with venous and arterial thrombosis, how it affects pregnancy outcomes, and testing.
Karlyn A, Martin, Mary, Cushman
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This JAMA Insights explores factor V Leiden, an inherited thrombophilia, and its association with venous and arterial thrombosis, how it affects pregnancy outcomes, and testing.
Karlyn A, Martin, Mary, Cushman
openaire +3 more sources
Thrombosis and Haemostasis, 2013
SummaryFactor V Leiden is a procoagulant mutation associated with venous and arterial thrombosis and pregnancy complications. Its high prevalence of 5% in Caucasians suggests that there are evolutionary benefits as well. Carriers are indeed reported to have various advantageous phenotypes related to haemostasis, inflammation and fertility: less acute ...
Thijs E, van Mens +2 more
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SummaryFactor V Leiden is a procoagulant mutation associated with venous and arterial thrombosis and pregnancy complications. Its high prevalence of 5% in Caucasians suggests that there are evolutionary benefits as well. Carriers are indeed reported to have various advantageous phenotypes related to haemostasis, inflammation and fertility: less acute ...
Thijs E, van Mens +2 more
openaire +3 more sources
Homozygous factor V Leiden and double heterozygosity for factor V Leiden and prothrombin mutation
Journal of Thrombosis and Thrombolysis, 2012The most common forms of familial thrombophilia are factor V Leiden (FVL) and prothrombin mutation (PTM). Homozygous FVL and PTM have long been feared conditions thought to cause high rates of morbidity and mortality. To analyse clinical features in patients with homozygous FVL and PTM, as well as patients with double heterozygosity for FVL and PTM ...
Ymir, Saemundsson +3 more
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World distribution of factor V Leiden.
Lancet, The, 1996N. Dzimiri, B. Meyer
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Dimensions of critical care nursing : DCCN, 2022
Background Factor V Leiden (FVL) is a hereditary thrombophilia, which causes the blood to be more hypercoagulable; in essence, the blood tends to clot more easily, especially under certain circumstances.
Morgan Morrow, Donna Lynch-Smith
semanticscholar +1 more source
Background Factor V Leiden (FVL) is a hereditary thrombophilia, which causes the blood to be more hypercoagulable; in essence, the blood tends to clot more easily, especially under certain circumstances.
Morgan Morrow, Donna Lynch-Smith
semanticscholar +1 more source