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CONGENITAL DEFICIENCY OF FACTOR VII
Australasian Annals of Medicine, 1958SummaryLaboratory investigations are described in a female patient who suffers from a congenital hæmorrhagic disorder due to deficiency of Factor VII. The one‐stage prothrombin time using brain extract was greatly prolonged, but using viper venom was normal. All tests of the intrinsic blood coagulation mechanism, including the thromboplastin generation
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The coagulation factor VII in pregnancy
British Journal of Haematology, 1984Summary. The hypercoagulable state in pregnancy is partly caused by the increased activity of factor VII in plasma. We demonstrate here that this activity is reduced to levels similar to those in plasma from non‐pregnant women by highly purified phospholipase C from Bacillus cereus, i.e.
Hans Prydz, Knut Dalaker
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Electroimmunoassay of factor VII antigen
Thrombosis Research, 1986A clear precipitating arc of factor VII antigen appeared by immunoelectrophoresis using 125I-labelled anti-factor VII antibody incorporated in the Laurell plate to enhance the sensitivity. A plasma sample could be electrophoresed directly on 1% agarose containing 1% rabbit anti-human factor VII antiserum, 0.1% 125I-labelled anti-human factor VII ...
O. Takamiya, K. Yoshioka, S. Kinoshita
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Cells and the Activation of Factor VII
Pathophysiology of Haemostasis and Thrombosis, 1996Binding of factor VII to tissue factor (TF) present on or released from cells initiates TF-dependent coagulation in vivo. Earlier data obtained with relipidated TF suspensions led to the hypothesis that all factor VII bound to limiting TF sites exposed after tissue injury could be rapidly activated to Vila/ TF complexes by low concentrations of factor ...
Samuel I. Rapaport, L. Vijaya Mohan Rao
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Biological Control of Factor VII
Thrombosis and Haemostasis, 1976SummaryThe tissue factor pathway is initiated by factor VII in the presence of tissue factor. The first proteolytic reaction involves cleavage of factor X by factor VII. Activated factor X, the product of this reaction, can activate factor VII by cleavage of a specific bond.
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1999
Factor VIIa, a vitamin K-dependent plasma serine protease, is the first enzyme in the coagulation cascade. The majority of this glycoprotein circulates as the inert zymogen (factor VII) with a concentration in pooled normal plasma of about 470 ng/ml (9.4 nmol/L)1.
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Factor VIIa, a vitamin K-dependent plasma serine protease, is the first enzyme in the coagulation cascade. The majority of this glycoprotein circulates as the inert zymogen (factor VII) with a concentration in pooled normal plasma of about 470 ng/ml (9.4 nmol/L)1.
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Nomenclature Recommendations for Factor VII
Thrombosis and Haemostasis, 1980Craig M. Jackson+2 more
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GENETIC VARIANTS OF FACTOR VII
The Lancet, 1972M. Samama, J. Conard, K.W.E. Denson
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