Results 11 to 20 of about 32,190 (255)
Acquired deficiency of coagulation factor VII
Revista Brasileira de Hematologia e Hemoterapia, 2015 Factor VII (FVII) is found in small amounts in plasma and has a very short half-life in circulation. FVII is vitamin K-dependently synthesized in the liver. As such, hepatopathies, vitamin K deficiency, or use of vitamin K antagonists is the cause of acquired deficiency.
Vanessa Afonso da Silva +2 more
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Seminars in Thrombosis and Hemostasis, 2009 The complex formed between the procoagulant serine protease activated factor VII (FVII) and the membrane protein tissue factor, exposed on the vascular lumen upon injury, triggers the initiation of blood clotting. This review describes the clinical picture of FVII deficiency and provides information on diagnosis and management of the disease.
G. Mariani, BERNARDI, Francesco
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Blood Coagulation & Fibrinolysis, 2002 As yet, there have been neither systematic reviews nor reports of randomized, controlled trials involving factor VII (FVII) deficiency. Hence, a picture of this disorder can only be drawn by reviewing and summarizing the data that is available. This article provides an overview of the understanding of this rare, inherited disorder of coagulation.
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Haematologica, 2013 Because of the very short half-life of factor VII, prophylaxis in factor VII deficiency is considered a difficult endeavor. The clinical efficacy and safety of prophylactic regimens, and indications for their use, were evaluated in factor VII-deficient ...
Mariasanta Napolitano +13 more
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Inhibitors to factor
Haemophilia, 2014 We performed a prospective study of FVII inhibitor occurrence in a large number of patients with FVII deficiency who had received replacement therapy for spontaneous or traumatic bleeding episodes, major or minor surgical interventions or prophylaxis.Inhibitor development was detected in 2.6% (3/115) of patients, but the incidence of de novo inhibitors
Batorova A +11 more
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Congenital factor VII deficiency presenting first time as isolated recurrent hematuria at late age
Saudi Journal of Kidney Diseases and Transplantation, 2019 Hematological conditions rarely present as isolated hematuria. Factor VII deficiency is a rare congenital coagulopathy inherited as autosomal recessive pattern. It usually presents a severe life-threatening bleeding at an early age.
Suman Sethi +5 more
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A case of intracranial hemorrhage in a neonate with congenital factor VII deficiency [PDF]
Korean Journal of Pediatrics, 2010 Congenital factor VII deficiency is a rare autosomal-recessive bleeding disorder. Bleeding manifestations and clinical findings vary widely, ranging from asymptomatic subjects to patients with hemorrhages that may cause significant handicaps.
Won Seok Lee, Young Sil Park
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Stem Cell Research, 2020 Factor VII (FVII) deficiency is the most common among the rare bleeding disorders, which is caused by mutations in coagulation factor VII. Clinical features caused by FVII deficiency vary from mild or asymptomatic to fatal cerebral hemorrhage.
Do-Hun Kim +3 more
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Clinical and Applied Thrombosis/Hemostasis, 2012 Congenital factor VII deficiency is the most common form of rare coagulation factor deficiencies. This article presents a retrospective evaluation of 73 factor VII deficiency cases that had been followed at our center. The study consisted of 48 males and 25 females (2 months-19 years). Thirty-one (42.5%) of them were asymptomatic.
Zafer, Salcioglu +7 more
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The Turkish Journal of Pediatrics, 2018 Intracranial hemorrhage is considered the most common cause of death in newborns with congenital factor VII (FVII) deficiency. Recombinant activated FVII (rFVIIa) provides specific replacement therapy, however there is limited experience with its ...
Zeynep İnce +5 more
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