Results 21 to 30 of about 32,190 (255)

Acquired factor VII deficiency causing severe bleeding disorder secondary to AL amyloidosis of the liver

Hematology Reports, 2018
A 52 year-old male presented with neck pain after undergoing thyroidectomy for a goiter three weeks prior which was complicated by a neck hematoma requiring evacuation.
Anthony L. Nguyen, Muhammad Kamal, Ravi Raghavan, Gayathri Nagaraj   +3 more
doaj   +1 more source

Impact of Rare Bleeding Disorders during Pregnancy on Maternal and Fetal Outcomes: Review of 29 Pregnancies at a Single Center [PDF]

Revista Brasileira de Ginecologia e Obstetrícia, 2017
Objective: This study aims to give information about the relationship between different types of factor deficiencies and maternal/obstetric outcomes. Methods We retrospectively reviewed the medical records of eight women with factor deficiency disorders.
Gokcen Orgul, Fatih Aktoz, M. Sinan Beksac   +2 more
doaj   +1 more source

Case of concurrent factor VII and factor XI deficiencies manifesting as spontaneous lower extremity compartment syndrome

Clinical Case Reports, 2022
Factor VII and XI deficiencies are rare bleeding disorders typically associated with mild or provoked bleeding. This case report describes a patient with factor VII and XI deficiencies with an unprovoked episode of lower extremity hematoma causing ...
Joseph P. Marshalek, David Yashar, Karen Huynh, Sarah Tomassetti   +3 more
doaj   +1 more source

Spontaneous subgaleal haemorrhage in a newborn: A rare presentation of congenital factor VII deficiency due to homogenous missense mutation of factor VII gene

Pediatric Hematology Oncology Journal, 2022
Background: Subgaleal haemorrhage (SGH) is an accumulation of blood between the aponeurosis and the periosteum following rupture of emissary veins. SGH is not uncommon in newborn with traumatic or instrumental delivery.
Ajoy Kumar Garg, Siva Chaitanya, S.K. Patnaik, Vivek Kumar   +3 more
doaj   +1 more source

Obscure gastrointestinal bleeding in a patient with factor VII deficiency: a case controlled with tranexamic acid [PDF]

Pediatric Emergency Medicine Journal
Factor VII deficiency is a rare, inherited coagulopathy, which can lead to prolonged bleeding. Here, we present a case report of an adolescent with factor VII deficiency who experienced small bowel bleeding that was successfully treated with tranexamic ...
Kyu Hwa Jeong, Young Bae Choi, Yu Bin Kim   +2 more
doaj   +1 more source

Factor VII deficiency-related recurrent hemarthrosis in a female child – When to suspect?

Iraqi Journal of Hematology, 2021
Recurrent hemarthrosis is a common entity in children. Although recurrent hemarthrosis most often associated with hemophilia (VIII or IX deficiency), but rarely it can be associated with factor VII deficiency (FVIID).
Siyaram Didel, Abhishek H. L. Purohit, Deepthi Krishna, Varuna Vyas, Kuldeep Singh   +4 more
doaj   +1 more source

Phenotypic and genotypic analysis of patients with congenital factor VII deficiency in a multicenter study in Thailand

Pediatric Hematology Oncology Journal, 2022
Objective: The phenotypic and genotypic analysis of patients with congenital factor VII deficiency were retrospectively conducted. Methods: The study included 26 patients defined as severe (n = 25) and moderate (n = 1) degree by FVII  T (38.3%), followed
Ampaiwan Chuansumrit, Surapan Parapakpenjune, Rungrote Natesirinilkul, Patcharee Komvilaisak, Werasak Sasanakul, Nongnuch Sirachainan, Anchalee Aramthienthamrong, Chorthip Wattanasutthipong, Kittima Kanchanakumhan, Kunrada Inthawong, Montana Chantaraniyom, Naonpan Pongpaothai, Nattaporntira Phalakornkul, Nisakorn Khumchan, Pacharapan Surapolchai, Panjarat Sowittayasakul, Somporn Wangruangsathit   +16 more
doaj   +1 more source

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

Chemotherapy for Spinal Cord Intramedullary Pediatric Low‐Grade Glioma—A Systematic Literature Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko, Segev Gabay, Jonathan Roth, Amit Ringel, Rina Dvir, Shlomi Constantini   +5 more
wiley   +1 more source

Evaluation of Clinical Features, Laboratory Findings and Treatment of Patients with Rare Factor Deficiency: A Retrospective Single Center Experience

Çocuk Dergisi, 2023
Objective: Patients with a rare factor deficiency (RFD) may be asymptomatic or present with life-threatening bleeding. Studies have shown no direct relationship between factor activity level and bleeding severity, with difficulties being experienced in ...
Işık Odaman Al, Tuba Hilkay Karapınar, Salih Gözmen, Yeşim Oymak   +3 more
doaj   +1 more source