Results 31 to 40 of about 278,057 (291)

Acquired factor VII deficiency causing severe bleeding disorder secondary to AL amyloidosis of the liver

Hematology Reports, 2018
A 52 year-old male presented with neck pain after undergoing thyroidectomy for a goiter three weeks prior which was complicated by a neck hematoma requiring evacuation.
Anthony L. Nguyen, Muhammad Kamal, Ravi Raghavan, Gayathri Nagaraj   +3 more
doaj   +1 more source

Impact of Rare Bleeding Disorders during Pregnancy on Maternal and Fetal Outcomes: Review of 29 Pregnancies at a Single Center [PDF]

Revista Brasileira de Ginecologia e Obstetrícia, 2017
Objective: This study aims to give information about the relationship between different types of factor deficiencies and maternal/obstetric outcomes. Methods We retrospectively reviewed the medical records of eight women with factor deficiency disorders.
Gokcen Orgul, Fatih Aktoz, M. Sinan Beksac   +2 more
doaj   +1 more source

Perinatal Gene Transfer to the Liver [PDF]

, 2011
The liver acts as a host to many functions hence raising the possibility that any one may be compromised by a single gene defect. Inherited or de novo mutations in these genes may result in relatively mild diseases or be so devastating that death within
Buckley, SM, Chan, JK, Howe, SJ, McKay, TR, Rahim, AA, Waddington, SN, Ward, NJ   +6 more
core   +1 more source

A viable mouse model of factor X deficiency provides evidence for maternal transfer of factor X. [PDF]

, 2008
BackgroundActivated factor X (FXa) is a vitamin K-dependent serine protease that plays a pivotal role in blood coagulation by converting prothrombin to thrombin. There are no reports of humans with complete deficiency of FX, and knockout of murine F10 is
Arruda, VR, Chu, K, Golden, JA, Herzog, RW, High, KA, Labosky, PA, Margaritis, P, Tai, SJ   +7 more
core   +2 more sources

Obscure gastrointestinal bleeding in a patient with factor VII deficiency: a case controlled with tranexamic acid [PDF]

Pediatric Emergency Medicine Journal
Factor VII deficiency is a rare, inherited coagulopathy, which can lead to prolonged bleeding. Here, we present a case report of an adolescent with factor VII deficiency who experienced small bowel bleeding that was successfully treated with tranexamic ...
Kyu Hwa Jeong, Young Bae Choi, Yu Bin Kim   +2 more
doaj   +1 more source

Spontaneous subgaleal haemorrhage in a newborn: A rare presentation of congenital factor VII deficiency due to homogenous missense mutation of factor VII gene

Pediatric Hematology Oncology Journal, 2022
Background: Subgaleal haemorrhage (SGH) is an accumulation of blood between the aponeurosis and the periosteum following rupture of emissary veins. SGH is not uncommon in newborn with traumatic or instrumental delivery.
Ajoy Kumar Garg, Siva Chaitanya, S.K. Patnaik, Vivek Kumar   +3 more
doaj   +1 more source

High Resolution Chandra Spectroscopy of Gamma Cassiopeia (B0.5IVe) [PDF]

, 2003
gamma Cas has long been famous for its unique hard X-ray characteristics. We report herein on a 53 ks Chandra HETGS observation of this target. An inspection of our spectrum shows that it is quite atypical for a massive star, with abnormally weak Fe XXV,
David H. Cohen, Doazan V., Harmanec P., Hony S., Kubo S., Ming Feng Gu, Myron A. Smith, Nancy Remage Evans, Owens A., Parmar A., Prudence G. Schran, Richard D. Robinson, Waters L. B.   +12 more
core   +3 more sources

Case of concurrent factor VII and factor XI deficiencies manifesting as spontaneous lower extremity compartment syndrome

Clinical Case Reports, 2022
Factor VII and XI deficiencies are rare bleeding disorders typically associated with mild or provoked bleeding. This case report describes a patient with factor VII and XI deficiencies with an unprovoked episode of lower extremity hematoma causing ...
Joseph P. Marshalek, David Yashar, Karen Huynh, Sarah Tomassetti   +3 more
doaj   +1 more source

Fiona’s FVII footprint

The Journal of Haemophilia Practice, 2020
Factor VII deficiency is a rare inheritable bleeding disorder that can be challenging to manage. Blood activity levels do not correlate with bleeding risk, and prophylaxis is a more difficult treatment option than for people with haemophilia due to the ...
Mulders Greta, Tuinhout Mirjam
doaj   +1 more source

Entering new areas in known fields: recombinant fusion protein linking recombinant factor VIIa with recombinant albumin (rVIIa-FP) – advancing the journey [PDF]

, 2016
The novel fusion protein linking recombinant factor VIIa with recombinant albumin (rVIIa-FP) is designed to extend the half-life of recombinant factor VIIa (rFVIIa) and improve the care of hemophilia A or B patients with inhibitors.
Legrand, Michel R, Preunkert, Suzanne, Weller, Rolf   +2 more
core   +1 more source