Results 61 to 70 of about 38,962 (211)
The use of recombinant factor VIIa in a pediatric septic shock patient with disseminated intravascular coagulation [PDF]
Einstein (São Paulo), 2008 This is a report on a pediatric patient with septic shock and disseminated intravascular coagulation, who developed life-threatening bleeding which was successfully treated with recombinant factor VIIa.
Ronaldo Arkader +2 more
doaj
Trombastenia de Glanzmann. Histerectomia vaginal de urgência tratada com factor VIIa recombinante.
Acta Médica Portuguesa, 2004 In the present article, regarding a clinical case of Thrombasthenia of Glanzmann with severe anaemia by menometrorrhagia, the authors propose the vaginal hysterectomy and the administration of the recombinant factor VIIa on the immediate pre and ...
João S Mairos +10 more
doaj +1 more source
Advanced Science, EarlyView.ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao +11 more
wiley +1 more source
Diffuse alveolar hemorrhage and recombinant factor VIIa treatment in pediatric patients [PDF]
Korean Journal of Pediatrics, 2016 Diffuse alveolar hemorrhage (DAH) is a life-threatening pulmonary complication in patients with hematologic malignancies or autoimmune disorders.
Jeong A Park
doaj +1 more source
Restoring Iron Homeostasis via Smoothened Inhibition: A Novel Strategy Against Hearing Loss
Advanced Science, EarlyView.. ABSTRACT Sensorineural hearing loss (SNHL) induced by noise or aminoglycoside antibiotics is a significant public health concern without any FDA‐approved pharmaceutical therapies. Dysregulation of iron homeostasis and its subsequently induced ferroptosis has increasingly been identified as a key mechanism underlying cochlear hair cell (HC) damage ...
Huanyu Mao +9 more
wiley +1 more source
In Silico Design of Novel Anticoagulant Peptides targeting Blood Coagulation Factor VIIa
Sultan Qaboos University Medical Journal, 2011 Objectives: The coagulation cascade initiated during vascular injury prevents bleeding. Unwanted clot formation is however detrimental and requires the use of anticoagulants for prophylaxis and treatment.
Manal S Q Al-Amri +3 more
doaj
Stroke intensive care: voice a view
Анналы клинической и экспериментальной неврологии, 2007 Modern methods of acute stroke treatment are analyzed: traditional and mechanical thrombolysis, intraventricular thrombolysis, recombinant activated factor VIIa for acute intracerebral hemorrhage, hemicraniectomy.
M. A. Piradov
doaj +1 more source
Advanced Science, EarlyView.Zmat1 deficiency mitigates pathological bone loss by impairing osteoclastogenesis and promoting osteoblastogenesis. Mechanistically, in osteoclasts, Zmat1 loss relieves transcriptional repression of the E3 ligase TRIM46, promoting YAP1 degradation and inhibiting osteoclastogenic genes.
Xinyu Chang +13 more
wiley +1 more source
Mediterranean Journal of Hematology and Infectious Diseases, 2014 Diffuse alveolar hemorrhage is a serious complication post stem cell transplantation with no proven definitive treatment, resulting in high mortality. Recombinant factor VIIa has been occassionaly used in such patients with good results. We report here a
Dharma Choudhary +3 more
doaj
Animal Models and Experimental Medicine, EarlyView.This schematic figure illustrates the experimental design and key findings of the study. Forty male C57BL/6 mice were assigned to either a standard diet control group or a cafeteria diet (CAFD) group for 16 weeks. CAFD induces obesity, insulin resistance (HOMA‐IR), hepatic steatosis, and dysregulation of a number of genes in visceral and subcutaneous ...
Guilherme Coutinho Kullmann Duarte +9 more
wiley +1 more source