Results 81 to 90 of about 16,284 (167)

Patient with congenital factor VII deficiency undergoing brain tumor neurosurgery successfully treated with recombinant factor VIIa and fresh frozen plasma: A case report and literature review. [PDF]

Medicine (Baltimore), 2023
Huang C, Yu Y, Zhai N, Mo W, Lin F.
europepmc   +1 more source

Management of a twin pregnancy patient with Glanzmann thrombasthenia might be caused by a novel ITGA2B gene mutation (c.2822G>A): a case report and family investigation

Platelets
Mutations in the ITGA2B or ITGB3 gene that encodes for the αIIbβ3 platelet integrin usually cause Glanzmann thrombasthenia (GT). This study aims to investigate the clinical characteristics of a pedigree exhibiting an inherited hemorrhagic disorder ...
Xiangcheng Liao, Ruikai Zhu, Zhigang Yang, Aiqiu Qin, Yucong Huang, Ping Li, Liling Liu, Zhuning Mo   +7 more
doaj   +1 more source

Pregnancy and Delivery Management With Recombinant Factor VIIa in a Glanzmann Thrombasthenia Patient: A Case Report. [PDF]

Cureus, 2022
Enciso L, Aragón-Mendoza RL, León LA, Torres-Torres CG.   +3 more
europepmc   +1 more source

Fatal scenario following dental extraction in middle‐aged man with history of acquired hemophilia: Employment of surgical tracheostomy and use of FFP and cryoprecipitate to gain patent airway

Clinical Case Reports
Key Clinical Message Acquired hemophilia A can upshot in a life‐threatening hemorrhage and airway obstruction. Airway bleeding is a weighty emergency in hemophilia care, necessitating the immediate start of effective hemostatic therapy (porcine factor ...
Sunil Bhatta MD, Sukriti Pandit MBBS, Sabin Nepal MD, Pratik Chaudhary MD   +3 more
doaj   +1 more source

Structure of human factor VIIa-soluble tissue factor with calcium, magnesium and rubidium. [PDF]

Acta Crystallogr D Struct Biol, 2021
Vadivel K, Schmidt AE, Cascio D, Padmanabhan K, Krishnaswamy S, Brandstetter H, Bajaj SP.   +6 more
europepmc   +1 more source

The Role of Tissue Factor and Factor VIIa in Hemostasis

Anesthesia & Analgesia, 2009
Tissue factor (TF) is a transmembrane receptor for Factor VII/VIIa (FVII/VIIa). It is constitutively expressed by cells surrounding blood vessels. The endothelium physically separates this potent “activator” from its circulating ligand FVII/FVIIa and prevents inappropriate activation of the clotting cascade. Breakage of the endothelial barrier leads to
openaire   +3 more sources

The Many Faces of Protease-Activated Receptor 2 in Kidney Injury

Biomedicines
Protease-activated receptor 2 (PAR2) is a seven-transmembrane, G-protein-coupled receptor that is activated by coagulation proteases such as factor VIIa and factor Xa and other serine proteases.
Yuji Oe, Tetsuhiro Tanaka, Nobuyuki Takahashi   +2 more
doaj   +1 more source

Factor VIIa treatment increases circulating extracellular vesicles in hemophilia patients: Implications for the therapeutic hemostatic effect of FVIIa. [PDF]

J Thromb Haemost, 2022
Das K, Pendurthi UR, Manco-Johnson M, Martin EJ, Brophy DF, Rao LVM.   +5 more
europepmc   +1 more source

Factor VIIa [PDF]

Science-Business eXchange, 2009
openaire   +1 more source

Thrombosis and recombinant factor VIIa [PDF]

Journal of Thrombosis and Haemostasis, 2004
openaire   +2 more sources