Results 71 to 80 of about 16,284 (167)
Salivary Extracellular Vesicles: Paradigm Shift in Liquid Biopsy Diagnostics
Journal of Extracellular Biology, Volume 5, Issue 7, July 2026.ABSTRACT Extracellular vesicles (EVs), lipid bilayer nanoparticles released by virtually all cells, serve as essential messengers for intercellular communication. Due to their involvement in several pathophysiological processes, EVs have recently gained considerable attention as potentially diagnostic and prognostic biomarkers for various illnesses ...
Kwanele Xulu +3 more
wiley +1 more source
Ischemia–Reperfusion Injury: Molecular Mechanisms and Therapeutic Interventions
MedComm, Volume 7, Issue 7, July 2026.Multiorgan ischemia–reperfusion injury begins with ischemia‐induced ATP depletion and ionic imbalance, followed by reperfusion‐triggered mitochondrial ROS/RNS bursts, regulated cell death, and DAMP release. Sterile inflammation converges on endothelial–immune–coagulation crosstalk, where NETs drive immunothrombosis, no‐reflow, and remote organ injury ...
Peng An +4 more
wiley +1 more source
De Novo Synthesis in Cancer Immunotherapy: Applications and Prospects
MedComm, Volume 7, Issue 7, July 2026.De novo protein design creates novel structures for cancer immunotherapy, integrating rational design principles like modularity and specificity. Leveraging computational tools, it optimizes cytokine engineering, adoptive cellular therapy, and checkpoint regulation to enhance antitumor immunity.
Yang Jin, Yanfeng Wu, Jianhua Luo
wiley +1 more source
Overview of the use of recombinant factor VIIa in children
Pediatric Health, Medicine and Therapeutics, 2014 John Puetz Department of Pediatrics, Division of Hematology/Oncology, Cardinal Glennon Children's Medical Center, Saint Louis University, St Louis, MO, USA Abstract: Recombinant factor VIIa (rFVIIa) was initially developed as a bypassing agent to ...
Puetz J
doaj
Journal of Pineal Research, Volume 78, Issue 4, July 2026.ABSTRACT Hearing impairment is attributed to factors such as age, genetic predisposition, and environmental influences, among which environmental factors are considered modifiable. Among various environmental factors, the role of poor lifestyle habits is particularly critical, yet the specific mechanisms by which they contribute to hearing damage ...
Siyu Qiu +4 more
wiley +1 more source
Tissue factor and factor VIIa – Hemostasis and beyond
Thrombosis Research, 2012 Initiation of the coagulation cascade via exposure of active tissue factor (TF) to blood and formation of the factor VIIa/TF complex is essential for hemostasis and is an initial procoagulant signal in thrombosis. As of early 2012, over 20,000 articles listed on PubMed describe advances in the understanding of TF biology in the settings of hemostasis ...
Alisa S, Wolberg, Alan E, Mast
openaire +3 more sources
Acta Clinica Croatica, 2015 We present the use of recombinant activated factor VIIa (rFVIIa) in a 6-month-old infant that suffered massive bleeding and subsequent coagulation disturbances during elective surgery for choroid plexus carcinoma in the lateral ventricle.
Alenka Spindler Vesel +6 more
doaj
Emergency cesarean section in glanzmann thrombasthenia: Anaesthetic management without recombinant factor VIIa. [PDF]
Saudi J Anaesth, 2023 Priyanka A, Arulprakasam S, Rudingwa P.
europepmc +1 more source
Factor VIIa releases phosphatidylserine-enriched extracellular vesicles from endothelial cells by activating acid sphingomyelinase. [PDF]
J Thromb Haemost, 2023 Das K +7 more
europepmc +1 more source
Pregnant Women with Severe Factor VII Deficiency Undergoing Cesarean Section Managed with a Short-Term Regimen of Recombinant Factor VIIa. [PDF]
Matern Fetal Med, 2023 Obore N +5 more
europepmc +1 more source