Acquired Factor VIII Deficiency Presenting as Gross Hematuria in a Hispanic, Pregnant Patient with Previously Undiagnosed Connective Tissue Disease [PDF]
Acquired factor VIII deficiency is a bleeding disorder caused by the presence of autoantibodies against clotting factor VIII. We report a case of a 24-year-old pregnant woman who presented with gross hematuria secondary to acquired factor VIII deficiency
Dulgheru, Emilia C.+2 more
core +3 more sources
Desmopressin in moderate hemophilia a patients: A treatment worth considering [PDF]
Desmopressin increases endogenous factor VIII levels in hemophilia A. Large inter-individual variation in the response to desmopressin is observed.
Beckers, E.+12 more
core +5 more sources
Minimal dataset for post-registration surveillance of new drugs in hemophilia: communication from the SSC of the ISTH [PDF]
Clinical ...
Collins, P.+7 more
core +3 more sources
Prolonged elevations in haemostatic and rheological responses following psychological stress in low socioeconomic status men and women [PDF]
Low socioeconomic status (SES) and psychological stress are associated with increased risk of coronary heart disease, and both may influence haemostatic responses.
Kunz-Ebrecht, S.+3 more
core +1 more source
Spontaneous bleeding in a patient with malignant lymphoma: A case of acquired hemophilia [PDF]
Background: Acquired hemophilia is a rare condition which can be associated with lymphoproliferative disease. Case Report: Eleven yea rs after the diagnosis of immunocytoma had been made, a 72-year-old man developed a high-titer factor VIII inhibitor. At
Brack, N.+5 more
core +1 more source
Successful elimination of factor VIII inhibitor using cyclosporin A [PDF]
No abstract ...
Dykes+10 more
core +1 more source
Isolation and primary cultures of human intrahepatic bile ductular epithelium [PDF]
A technique for the isolation of human intrahepatic bile ductular epithelium, and the establishment of primary cultures using a serum- and growth-factor-supplemented medium combined with a connective tissue substrata is described.
A. E. Sirica+24 more
core +1 more source
The effects of different alcoholic drinks on lipids, insulin and haemostatic and inflammatory markers in older men [PDF]
Light to moderate drinking is associated with lower risk of coronary heart (CHD) than non-drinkers. We have examined the relationships between total alcohol intake and type of alcoholic beverage and several potential biological mechanisms. We carried out
Lennon, L.+6 more
core +1 more source
Perioperative pharmacokinetic-guided factor VIII concentrate dosing in haemophilia (OPTI-CLOT trial):an open-label, multicentre, randomised, controlled trial [PDF]
Background Dosing of replacement therapy with factor VIII concentrate in patients with haemophilia A in the perioperative setting is challenging. Underdosing and overdosing of factor VIII concentrate should be avoided to minimise risk of perioperative ...
Beckers, E.A.+18 more
core +1 more source
Inhibitors in Patients with Congenital Bleeding Disorders Other Than Hemophilia [PDF]
The most worrying complication of replacement therapy for severe hemophilia A and B is currently the occurrence of inhibitory alloantibodies against infused factor VIII and factor IX, respectively.
Franchini, Massimo+6 more
core +1 more source