Results 161 to 170 of about 1,736,415 (259)

Preclinical development of TAK-754, a high-performance AAV8-based vector expressing coagulation factor VIII. [PDF]

Mol Ther Methods Clin Dev
Lengler J, Weiller M, Horling F, Mayrhofer J, Schuster M, Falkner FG, Gil-Farina I, Klugmann M, Scheiflinger F, Hoellriegl W, Rottensteiner H.   +10 more
europepmc   +1 more source

Impacts of Device Geometry and Layout on Temperature Profile during Large‐Area Photonic Curing

Advanced Engineering Materials, EarlyView.
The study investigates how gate geometry affects peak curing temperature during photonic curing of solution‐processed indium zinc oxide thin‐film transistors. Using 3D simulations and experimental validation, it reveals that larger gate areas and smaller aspect ratios increase curing temperature and thus improve transistor performance. Findings provide
Yasir Fatha Abed, Neel Chatterjee, Bing Luo, Sarah L. Swisher   +3 more
wiley   +1 more source

Efficacy and safety of recombinant porcine factor VIII in Japanese patients with acquired hemophilia A. [PDF]

Int J Hematol
Seki Y, Ogawa Y, Kikuchi T, Sakaida E, Mizuta Y, Kitagawa T, Takemura K, Miyaguchi Y, Nogami K, Matsushita T.   +9 more
europepmc   +1 more source

Scalable Fabrication of Height‐Variable Microstructures with a Revised Wetting Model

Advanced Engineering Materials, EarlyView.
Height‐variable microstructures are fabricated using a scalable CO2 laser machining approach, enabling precise control of wettability through structural gradients. Classical wetting models fail to capture height‐induced effects, necessitating a revised theoretical framework.
Prabuddha De Saram, Nam‐Trung Nguyen, Navid Kashaninejad   +2 more
wiley   +1 more source

Atomistic Mechanism of Lipid Membrane Binding for Blood Coagulation Factor VIII with Molecular Dynamics Simulations on a Microsecond Time Scale. [PDF]

J Phys Chem B
Avery NG, Childers KC, McCarty J, Spiegel PC.   +3 more
europepmc   +1 more source

Scalable Manufacturing of Radiation‐Tolerant Potentiometric Electrodes: A Systematic Transition from Laboratory to Semiautomated Fabrication

Advanced Engineering Materials, EarlyView.
Laboratory protocols for producing thin‐film pH electrodes for sterilized single‐use technologies have been successfully developed into a semiautomated workflow, with higher throughput and precision of membrane thickness. Accuracies are within 0.05 pH units versus ground truth, and uncertainty analysis reveals the largest sources of error to be derived
Bingyuan Zhao, Aiganym Yermembetova, Benson Kunhung Tsai, Jialong Huang, Alexander Wei   +4 more
wiley   +1 more source

From Nature to Engineering: Mortar Volume and Interfacial Mechanics in Bioinspired Ceramics

Advanced Engineering Materials, EarlyView.
Inspired by natural armors like nacre, this study explores how varying the volume fraction of the soft mortar layer impacts the interfacial strength and toughness of bioinspired ceramics. Experimental and computational analysis reveals that higher mortar volumes increase energy dissipation but reduce interfacial stiffness, offering insights for ...
Ehsan Azad, Hamidreza Yazdani Sarvestani, Behnam Ashrafi, Farjad Shadmehri, Mehdi Hojjati   +4 more
wiley   +1 more source

Factor VIII moiety of recombinant Factor VIII Fc fusion protein impacts Fc effector function and CD16⁺ NK cell activation. [PDF]

Front Immunol
Lagassé HAD, Ou J, Sauna ZE, Golding B.
europepmc   +1 more source

Influence of a Standard Heat Treatment on the Microstructure and Properties of Inconel X‐750 Produced by Laser Powder Bed Fusion

Advanced Engineering Materials, EarlyView.
Ni‐base superalloys produced using additive manufacturing (AM) have a different response to heat treatments when compared to their conventional counterparts. Due to such unpredictability, various alloys with industrial interest are currently overlooked in most prior AM research.
Guilherme Maziero Volpato, Adriano de Souza Pinto Pereira, Steffen Neumeier, Dachamir Hotza, Mathias Göken, Ulrich Tetzlaff, Márcio Celso Fredel   +6 more
wiley   +1 more source