ICU‐EEG Pattern Detection by a Convolutional Neural Network
ABSTRACT Objective Patients in the intensive care unit (ICU) often require continuous EEG (cEEG) monitoring due to the high risk of seizures and rhythmic and periodic patterns (RPPs). However, interpreting cEEG in real time is resource‐intensive and heavily relies on specialized expertise, which is not always available.
Giulio Degano +5 more
wiley +1 more source
Half‐life extended factor VIII for the treatment of hemophilia A
A. Tiede
semanticscholar +1 more source
Long‐Term Evaluation of Givinostat in Duchenne Muscular Dystrophy, and Natural History Comparisons
ABSTRACT Objectives This ongoing, open‐label extension study is evaluating the long‐term safety, tolerability, and efficacy of givinostat, a Class I and II histone deacetylase inhibitor, in patients with Duchenne muscular dystrophy (DMD). Methods The recruited patients completed one of two prior clinical studies (one Phase 2 and one Phase 3 [EPIDYS ...
Craig M. McDonald +74 more
wiley +1 more source
Importancia del diagnóstico de portadoras en familias con antecedentes de hemofilia
La hemofilia es una enfermedad hemorrágica hereditaria ligada al cromosoma X que se presenta debido a mutaciones en los genes del factor VIII (hemofilia A) y el factor IX (hemofilia B), que ocasiona una disminución o deficiencia funcional de estas ...
Kalia Lavaut Sánchez
doaj
Exorcizing the devil of factor VIII inhibitors. [PDF]
Moorehead PC.
europepmc +1 more source
Inhibition of Human Platelet Aggregation by Plasmin Digests of Human and Bovine Fibrinogen Preparations: Role of Contaminating Factor VIII-related Material [PDF]
Dolly Culasso +4 more
openalex +1 more source
Durability of Response to B‐Cell Maturation Antigen‐Directed mRNA Cell Therapy in Myasthenia Gravis
ABSTRACT Objective We report the 12‐month follow‐up outcomes from a Phase 2 clinical trial (NCT04146051) evaluating Descartes‐08, a BCMA‐directed RNA chimeric antigen receptor T‐cell (rCAR‐T) therapy for refractory generalized myasthenia gravis (MG).
Nizar Chahin +10 more
wiley +1 more source
Spontaneous Inhibitors of Factor VIII (Antihemophilic Factor) [PDF]
Fereydoun Ala +1 more
doaj +1 more source
Estimating the Factor VIII-Equivalent Activity of Emicizumab Using Global Assays of Haemostasis. [PDF]
Kraemmer D +6 more
europepmc +1 more source
Practice Recommendations for Genetic Testing of Ataxias
ABSTRACT Objective Over the past decade, significant advances in genetic testing for ataxia have improved diagnostic accuracy, informed clinical trial eligibility, guided treatment decisions, and enabled cascade testing of at‐risk relatives. While guidance exists for other neurogenetic conditions, there are no standardized guidelines on genetic ...
Sharan R. Srinivasan +7 more
wiley +1 more source

