Results 201 to 210 of about 257,618 (243)

Characterization and Optimization of Vesicle Properties in bioPISA: from Size Distribution to Post‐Assembly Loading

Advanced Biology, EarlyView.
The paper explores the creation and characterization of vesicles through biocatalytic Polymerization‐Induced Self‐Assembly (bioPISA), focusing on achieving size uniformity using centrifugation techniques. It examines the effects of stirring speed on vesicle morphology and analyses the internal polymer‐rich structure using fluorescence correlation ...
Andrea Belluati, Adrian Bloch, Kaloian Koynov, Mariana Müller Nieva, Mohadeseh Bagherabadi, Annette Andrieu‐Brunsen, Harald Kolmar, Nico Bruns   +7 more
wiley   +1 more source

Thrombin generation to evaluate the complex hemostatic balance of hemophilia A plasma containing direct oral anticoagulant and supplemented by factor VIII. [PDF]

Res Pract Thromb Haemost
Lamoine S, Jury V, Fourneyron V, Douxfils J, Teissandier D, Talon L, Sinegre T, Lebreton A.   +7 more
europepmc   +1 more source

Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics

Advanced Biology, EarlyView.
This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim, Kanghoon Choi, Amy Lin, Jungkyu Kim   +3 more
wiley   +1 more source

Corrigendum to "Real-world use of recombinant porcine sequence factor VIII in the treatment of acquired hemophilia A: EU PASS". [PDF]

Ther Adv Hematol
europepmc   +1 more source

Pre-clinical evaluation of an enhanced-function factor VIII variant for durable hemophilia A gene therapy in male mice. [PDF]

Nat Commun
Sternberg AR, Martos-Rus C, Davidson RJ, Liu X, George LA.   +4 more
europepmc   +1 more source

Activation of SIRT1 Reduces Renal Tubular Epithelial Cells Fibrosis in Hypoxia Through SIRT1‐FoxO1‐FoxO3‐Autophagy Pathway

Advanced Biology, EarlyView.
Hypoxia promotes the epithelial‐mesenchymal transition (EMT) of renal tubular epithelial cells via the SIRT1‐FoxO1‐FoxO3‐autophagy pathway, thereby resulting in the fibrosis of renal tubular epithelial cells. Activation of SIRT1 or induction of autophagy inhibits this process, alleviating hypoxia‐induced fibrosis.
Guangyu Wang, Lijuan Zhang, Jiaorong Tan, Fei Li, Yishan Jin, Limei He, Xin Yang   +6 more
wiley   +1 more source

Scaling Up Synthetic Cell Production Using Robotics and Machine Learning Toward Therapeutic Applications

Advanced Biology, EarlyView.
Synthetic cells (SCs) hold great promise for biomedical applications, but manual production limits scalability. This study presents an automated method for large‐scale SC synthesis, integrating robotic liquid handling and machine learning‐driven high‐throughput characterization.
Noga Sharf‐Pauker, Ido Galil, Omer Kfir, Gal Chen, Rotem Menachem, Jeny Shklover, Avi Schroeder, Shanny Ackerman   +7 more
wiley   +1 more source

Efficacy of emicizumab in patients with severe haemophilia A without factor VIII inhibitors in Germany: evaluation of real-life data documented by the smart medication eDiary. [PDF]

Ther Adv Hematol
Escuriola Ettingshausen C, Eberl W, Eichler H, Fischer R, Hart C, Holstein K, Knöfler R, Kreutz J, Kühnöl CD, Miesbach WA, Pfrepper C, Rösch A, Sachs UJ, Trautmann-Grill K, Mondorf W.   +14 more
europepmc   +1 more source