Attempted spleen transplant in classical hemophilia [PDF]
Recent evidence has indicated that the spleen may be partly responsible for synthesis or storage of antihemophilic factor (factor VIII) in dogs (8) and in man (2). Transplantation of the spleen into dogs with congenital deficiency of factor VIII has been
Githens, JH+5 more
core +1 more source
Recombinant factor VIIa concentrate versus plasma-derived concentrates for treating acute bleeding episodes in people with haemophilia and inhibitors [PDF]
In people with haemophilia, therapeutic clotting agents might be recognised as a foreign protein and induce anti-factor VIII antibodies, known as 'inhibitors'.
D'AMICO, Roberto+4 more
core +1 more source
Scale-factor duality in string Bianchi cosmologies [PDF]
We apply the scale factor duality transformations introduced in the context of the effective string theory to the anisotropic Bianchi-type models. We find dual models for all the Bianchi-types [except for types $VIII$ and $IX$] and construct for each of ...
Copeland E. J.+3 more
core +4 more sources
The Role of ABO Blood Type in Thrombosis Scoring Systems [PDF]
In addition to their major role in transfusion medicine, there is increasing evidence that ABO blood group antigens (complex carbohydrate molecules widely expressed on the surface of red blood cells and several other cell types) are implicated in the ...
Catalano, Liviana+5 more
core +1 more source
This study examines the demographic dynamics of two seabird populations on Tromelin Island, 15 years after the eradication of brown rats. The results indicate that these populations are in good health and are expected to continue growing until breeding sites are saturated in about a century.
Merlène Saunier+6 more
wiley +1 more source
Angiogenesis in Squamous Cervical Neoplasia: Comparative Study of two Endothelial Cells [PDF]
Purpose: to compare the efficiency of anti-factor VIII and anti-CD34 antibodies as vascular makers in cervical cancer, in cervical intraepithelial neoplasia and in normal cervix.
Baracat, Edmund Chada+4 more
core +5 more sources
Making tau amyloid models in vitro: a crucial and underestimated challenge
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Suzaku Reveals Helium-burning Products in the X-ray Emitting Planetary Nebula BD+303639 [PDF]
BD+303639, the brightest planetary nebula at X-ray energies, was observed with Suzaku, an X-ray observatory launched on 2005 July 10. Using the X-ray Imaging Spectrometer, the K-lines from C VI, O VII, and O VIII were resolved for the first time, and C/O,
Cahn J.+14 more
core +3 more sources
Acquired Factor VIII Deficiency Presenting as Gross Hematuria in a Hispanic, Pregnant Patient with Previously Undiagnosed Connective Tissue Disease [PDF]
Acquired factor VIII deficiency is a bleeding disorder caused by the presence of autoantibodies against clotting factor VIII. We report a case of a 24-year-old pregnant woman who presented with gross hematuria secondary to acquired factor VIII deficiency
Dulgheru, Emilia C.+2 more
core +2 more sources
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek+15 more
wiley +1 more source