Results 91 to 100 of about 12,705,637 (166)

Current Closure and Joule Heating in Data‐Driven 3‐D Auroral Arc Simulations

open access: yesJournal of Geophysical Research: Space Physics, Volume 130, Issue 11, November 2025.
Abstract Discrete auroral arc systems, despite many symmetries, are three‐dimensional in nature, encapsulating latitude and longitude variations in precipitation and field‐aligned currents combined with important altitude variations in conductivities, hence closure currents.
J. van Irsel   +6 more
wiley   +1 more source

Diagnostics of Autoimmune Hepatitis Enabled by Non‐Invasive Clinical Proteomics

open access: yesAlimentary Pharmacology &Therapeutics, Volume 62, Issue 9, Page 901-919, November 2025.
Mass‐spectrometry‐based proteomic analyses of paired liver‐plasma samples from patients with AIH enabled discovery of numerous proteins showing high diagnostic accuracy. Proteomics may constitute a novel non‐invasive diagnostic tool for AIH if validated in larger, age‐ and sex‐matched cohorts.
Anne‐Sofie Houlberg Jensen   +20 more
wiley   +1 more source

Post‐Viral Acquired Idiopathic Purpura Fulminans Caused by Anti‐Protein S Antibodies

open access: yesActa Paediatrica, Volume 114, Issue 10, Page 2511-2517, October 2025.
ABSTRACT Acquired Idiopathic purpura fulminans is a rare pathology caused by anti‐protein S antibodies. We have conducted a literature review focusing on the most recent developments in diagnosis and management. Diagnosis is based on the demonstration of typical necrotic purpura lesions on the legs. Treatment must be initiated without delay by infusion
Alexandre Theron   +2 more
wiley   +1 more source

Hemofilia A adquirida Acquired hemophilia A

open access: yesRevista Cubana de Hematología, Inmunología y Hemoterapia, 2010
La hemofilia A adquirida (HAA) es un trastorno hemorrágico poco frecuente caracterizado por la presencia de autoanticuerpos contra el factor VIII (FVIII) circulante.
Delfina Almagro Vázquez
doaj  

Spotlight on emicizumab in the management of hemophilia A: patient selection and special considerations

open access: yesJournal of Blood Medicine, 2019
Koji Yada, Keiji NogamiDepartment of Pediatrics, Nara Medical University, Kashihara, Nara, JapanAbstract: Emicizumab is a factor (F)VIIIa-mimicking bispecific antibody recognizing FIXa and FX molecules.
Yada K, Nogami K
doaj  

Altered Interactions between the A1 and A2 Subunits of Factor VIIIa following Cleavage of A1 Subunit by Factor Xa*

open access: yesJournal of Biological Chemistry, 2003
Factor VIIIa consists of subunits designated A1, A2, and A3-C1-C2. The limited cofactor activity observed with the isolated A2 subunit is markedly enhanced by the A1 subunit.
K. Nogami   +3 more
semanticscholar   +1 more source

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