Current Closure and Joule Heating in Data‐Driven 3‐D Auroral Arc Simulations
Abstract Discrete auroral arc systems, despite many symmetries, are three‐dimensional in nature, encapsulating latitude and longitude variations in precipitation and field‐aligned currents combined with important altitude variations in conductivities, hence closure currents.
J. van Irsel +6 more
wiley +1 more source
Diagnostics of Autoimmune Hepatitis Enabled by Non‐Invasive Clinical Proteomics
Mass‐spectrometry‐based proteomic analyses of paired liver‐plasma samples from patients with AIH enabled discovery of numerous proteins showing high diagnostic accuracy. Proteomics may constitute a novel non‐invasive diagnostic tool for AIH if validated in larger, age‐ and sex‐matched cohorts.
Anne‐Sofie Houlberg Jensen +20 more
wiley +1 more source
Post‐Viral Acquired Idiopathic Purpura Fulminans Caused by Anti‐Protein S Antibodies
ABSTRACT Acquired Idiopathic purpura fulminans is a rare pathology caused by anti‐protein S antibodies. We have conducted a literature review focusing on the most recent developments in diagnosis and management. Diagnosis is based on the demonstration of typical necrotic purpura lesions on the legs. Treatment must be initiated without delay by infusion
Alexandre Theron +2 more
wiley +1 more source
Hemofilia A adquirida Acquired hemophilia A
La hemofilia A adquirida (HAA) es un trastorno hemorrágico poco frecuente caracterizado por la presencia de autoanticuerpos contra el factor VIII (FVIII) circulante.
Delfina Almagro Vázquez
doaj
Koji Yada, Keiji NogamiDepartment of Pediatrics, Nara Medical University, Kashihara, Nara, JapanAbstract: Emicizumab is a factor (F)VIIIa-mimicking bispecific antibody recognizing FIXa and FX molecules.
Yada K, Nogami K
doaj
Factor VIIIa consists of subunits designated A1, A2, and A3-C1-C2. The limited cofactor activity observed with the isolated A2 subunit is markedly enhanced by the A1 subunit.
K. Nogami +3 more
semanticscholar +1 more source
The role of amino-terminal residues of the heavy chain of factor IXa in the binding of its cofactor, factor VIIIa [PDF]
Nobuko Hamaguchi +3 more
openalex +1 more source
Depolymerized holothurian glycosaminoglycan with novel anticoagulant actions: antithrombin III- and heparin cofactor II-independent inhibition of factor X activation by factor IXa-factor VIIIa complex and heparin cofactor II-dependent inhibition of thrombin [PDF]
Hideki Nagase +6 more
openalex +1 more source
Binding studies of the enzyme (factor IXa) with the cofactor (factor VIIIa) in the assembly of factor-X activating complex on the activated platelet surface [PDF]
Shafeeque Ahmad +2 more
openalex +1 more source
A Proposed Solution Structural Model for Human Coagulation Tenase Complex between Factor VIIIa and IXa: A Protein-Protein Docking and MD Refinement Study [PDF]
Divi Venkateswarlu
openalex +1 more source

