Self-assembling linear and star shaped poly (ε-caprolactone)/poly[(meth)acrylic acid] block copolymers as carriers of indomethacin and quercetin [PDF]
A amphiphilic linear AB, BAB, and star shaped (AB)(3) block copolymers of poly(E-caprolactone) (PCL)/poly(meth)acrylic acid (P(M)AA) are used for the preparation of nanoparticles and drug entrapment, where indomethacin and quercetin are employed as model
Bury, Katarzyna+2 more
core +2 more sources
Activated protein C exerts its anticoagulant activity by protein S-dependent inactivation of factors Va and VIIIa by limited proteolysis. We identified a venous thrombosis patient who has plasma protein C antigen level of 63% and activity levels of 44 ...
Yeling Lu+6 more
doaj +1 more source
The influence of expertise on brain activation of the action observation network during anticipation of tennis and volleyball serves [PDF]
In many daily activities, and especially in sport, it is necessary to predict the effects of others' actions in order to initiate appropriate responses.
Balser, N+8 more
core +1 more source
The influence of transition metal solutes on dislocation core structure and values of Peierls stress and barrier in tungsten [PDF]
Several transition metals were examined to evaluate their potential for improving the ductility of tungsten. The dislocation core structure and Peierls stress and barrier of $1/2<111>$ screw dislocations in binary tungsten-transition metal alloys (W$_{1-x}$TM$_{x}$) were investigated using first principles electronic structure calculations.
arxiv +1 more source
Cerebral gray matter volume in patients with chronic migraine: correlations with clinical features [PDF]
Background To date, few MRI studies have been performed in patients affected by chronic migraine (CM), especially in those without medication overuse.
Ambrosini, Anna+13 more
core +2 more sources
A comprehensive approach in performance evaluation for modernreal-time operating systems [PDF]
In real-time computing the accurate characterization of the performance and determinism that a particular real-time operating system/hardware combination can provide for real-time applications is essential.
Conde, Jesús F.+2 more
core +2 more sources
It's all in the eyes: subcortical and cortical activation during grotesqueness perception in autism [PDF]
Atypical face processing plays a key role in social interaction difficulties encountered by individuals with autism. In the current fMRI study, the Thatcher illusion was used to investigate several aspects of face processing in 20 young adults with high ...
Donnelly, Nick+7 more
core +2 more sources
Exploring potential anticoagulant drug formulations using thrombin generation test
Many anticoagulant drugs inhibiting proteins of the coagulation cascade have been developed. The main targets of anticoagulant drugs are thrombin and factor Xa; inhibiting these factors delays thrombus growth, thus preventing thrombosis while increasing ...
Elena Zavyalova, Alexey Kopylov
doaj +1 more source
Score predictor factor analysis: Reproducing observed covariances by means of factor score predictors [PDF]
The model implied by factor score predictors does not reproduce the non-diagonal elements of the observed covariance matrix as well as the factor loadings. It is therefore investigated whether it is possible to estimate factor loadings for which the model implied by the factor score predictors optimally reproduces the non-diagonal elements of the ...
arxiv +1 more source
The goal of these studies was to extensively characterize the first recombinant FIX therapeutic corresponding to the threonine-148 (Thr-148) polymorph, IXINITY (trenonacog alfa [coagulation factor IX (recombinant)]).
Dougald M. Monroe+4 more
doaj +1 more source