Results 101 to 110 of about 12,470,244 (276)

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Hemophilia B with Mutations at Glycine-48 of Factor Ix Exhibited Delayed Activation by the Factor Viia-Tissue Factor Complex

open access: yes, 2009
Gly-48 is in the conserved DGDQC sequence (residues 47-51 of human factor IX) of the first EGF (EGF-1)-like domain of factor IX. The importance of the Gly-48 is manifested by two hemophilia B patients; factor IX & subTainan; and factor IXsubMalmö27;
WU, PEI-CHIH;HAMAGUCHI NOBUKO;LIN, CHIA-NIE;SHEN, MING-CHING;LIN, SHU-WHA   +1 more
core  

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

open access: yesFEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park   +8 more
wiley   +1 more source

Self-association of complement factor H in the presence and absence of metals [PDF]

open access: yes, 2010
In the complement system of innate immunity, factor H (FH) is a major regulator of its activation, and is comprised of 20 short complement regulator (SCR) domains.
Nan, R.
core  

PENENTUAN SENSITIVITAS DETEKTOR SINAR-X BERBASIS FOTOTRANSISTOR

open access: yes, 2016
X-ray interaction with matter can produce phenomenon of fluorescence that emits visible light. This phenomenon was exploited to design an x-ray detector based on phototransistor by attaching a screen ZnS(Ag) on the surface of the phototransistor which is
Fardela, Ramacos; Teknik Komputer-Sekolah Tinggi Teknologi Payakumbuh
core   +1 more source

Anticoagulation in atrial fibrillation with factor X deficiency—A management dilemma

open access: yesClinical Case Reports, 2018
Key Clinical Message Factor X (FX) deficiency is a rare bleeding disorder. There is currently no clear guideline or recommendation for the appropriate selection of anticoagulation and management of patients with FX deficiency who require anticoagulation.
Jian Liang Tan   +3 more
doaj   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

open access: yesFEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan   +4 more
wiley   +1 more source

Complement Factor H: solution structures and interactions with ligands [PDF]

open access: yes, 2009
Factor H (FH) is a plasma glycoprotein that plays a central role in regulating the alternative pathway of complement. It is composed of 20 short complement regulator (SCR) domains.
Okemefuna, A.I.
core  

Factor X phenomenon

open access: yes, 1959
Storage of human serum at refrigerator temperature yields a reagent which poorly supports thromboplastin generation. Although the degree of this defect showed no correlation with the serum prothrombin content, a high serum prothrombin was found to ...
Mona Kropatkin, Theodore H. Spaet
core   +1 more source

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