Results 111 to 120 of about 9,057,173 (269)

Association of genetic variations in ACE2, TIRAP and factor X with outcomes in COVID-19. [PDF]

PLoS One, 2022
Traets MJM, Nijhuis RHT, Morré SA, Ouburg S, Remijn JA, Blok BA, de Laat B, Jong E, Herder GJM, Fiolet ATL, Verweij SP.   +10 more
europepmc   +1 more source

Activation of coagulation factor X by insoluble trypsin [PDF]

, 1971
ROY M. HOWELL, R J Dupe
openalex   +1 more source

ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee, Keyue Chen, Ryan Loke, Xiang Li, David Liubart, Golam T. Saffi, Jonathan T. S. Chow, Ché M. P. Melo, Lydia To, Leonardo Salmena   +9 more
wiley   +1 more source

Stoichiometric analysis reveals a unique phosphatidylserine binding site in coagulation factor X. [PDF]

J Thromb Haemost, 2022
Paul D, Morrissey JH.
europepmc   +1 more source

International Union of Crystallography Commission on Crystallographic Apparatus. Accuracy of structure factors from X-ray powder intensity measurements [PDF]

, 1977
P. Suortti, L. D. Jennings
openalex   +1 more source

Raphin‐1 mediates the survival and sensitivity to radiation of pediatric‐type diffuse high‐grade glioma via phosphorylated eukaryotic initiation factor 2α‐dependent and ‐independent processes

Molecular Oncology, EarlyView.
Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan, Moshe Leitner, Amos Toren, Shoshana Paglin, Michal Yalon   +4 more
wiley   +1 more source

Unexpected Dynamic Binding May Rescue the Binding Affinity of Rivaroxaban in a Mutant of Coagulation Factor X. [PDF]

Front Mol Biosci, 2022
Zhang ZL, Chen C, Qu SY, Ding Q, Xu Q.
europepmc   +1 more source

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

Molecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella, Giuseppina Comito, Luigi Ippolito, Erica Pranzini, Marta Iozzo, Giulia Gangarossa, Francesca Virgilio, Silvia Bua, Alessio Nocentini, Giada Sandrini, Nicla Lorito, Marina Bacci, Gabriella Nesi, Pietro Spatafora, Sergio Serni, Claudiu T. Supuran, Andrea Morandi, Paola Chiarugi, Elisa Giannoni   +18 more
wiley   +1 more source

A Rare Cause of Acquired Factor X Deficiency in an 87-Year-Old Female. [PDF]

Case Rep Hematol, 2021
Bangolo A, Waykole T, Niazi B, Sajja C, Akhter M, Gupta B, Elias S.   +6 more
europepmc   +1 more source

Studies on Gonococcus Infection X. Pili and Leukocyte Association Factor as Mediators of Interactions Between Gonococci and Eukaryotic Cells In Vitro [PDF]

, 1975
J Swanson, Edward Sparks, Dallan Young, Gretchen King   +3 more
openalex   +1 more source