Results 261 to 270 of about 1,008,107 (310)
Some of the next articles are maybe not open access.
Factor X deficiency and pregnancy
BMJ Case ReportsFactor X (FX) is a vitamin K-dependent enzyme, which acts as an important coagulation factor of coagulation cascade. FX deficiency is an autosomal recessive inherited disease and is often demonstrated in families with consanguity. Pregnancy in women with congenital FX deficiency has been associated with adverse fetal outcomes.
Seema Chigateri +3 more
openaire +2 more sources
JAMA, 1974
Isolated factor X deficiency in association with abnormal plasma antithrombin activity was recognized in a 59-year-old man with amyloidosis and signs and symptoms of calf pain suggestive of thrombophlebitis. Venographic studies excluded venous thrombosis, and, despite major coagulation abnormalities, there was no hemorrhagic tendency.
openaire +1 more source
Isolated factor X deficiency in association with abnormal plasma antithrombin activity was recognized in a 59-year-old man with amyloidosis and signs and symptoms of calf pain suggestive of thrombophlebitis. Venographic studies excluded venous thrombosis, and, despite major coagulation abnormalities, there was no hemorrhagic tendency.
openaire +1 more source
Replacement therapy for congenital Factor X deficiency
Transfusion, 1985We studied a young woman with severe (< 1%) congenital factor X deficiency during a 2‐year period in order to document the levels of factor X required to provide hemostasis for vaginal bleeding, epistaxis, and hemarthroses, as well as during surgery.
R D, Knight, C F, Barr, B M, Alving
openaire +2 more sources
Acquired Factor X Deficiency and Amyloidosis
American Journal of Clinical Pathology, 1977A selective acquired Factor X deficiency is an unusual occurrence. Six cases of an acquired Factor X deficiency in association with amyloidosis have been reported. This paper describes two additional cases, suggesting that this relationship may be more than coincidental.
openaire +2 more sources
Treatment of Amyloidosis Associated Factor X Deficiency
Thrombosis and Haemostasis, 1976SummaryThis is the tenth patient in thirteen years to be reported with the findings of an isolated factor X deficiency associated with primary amyloidosis. A favorable response to factor IX concentrate was manifested by temporary clinical and laboratory correction of her diathesis.
J A, Spero +3 more
openaire +2 more sources
Factor X Deficiency and Systemic Amyloidosis
New England Journal of Medicine, 1977The association of an isolated acquired factor X (Stuart-factor) deficiency and systemic acquired amyloidosis has been sporadically reported over the last 15 years,1 , 2 and over two thirds of the ...
openaire +2 more sources
Systemic Amyloidosis Associated With Factor X Deficiency
Acta Pathologica Japonica, 1984An autopsy case of amyloidosis associated with factor X deficiency is reported. The patient showed a markedly decreased level of factor X (9% normal) and an extremely shortened half‐life of intravenously infused factor X. Amyloid deposition was present in most of the visceral organs with special involvement of the liver and spleen.
H, Shibuya +4 more
openaire +2 more sources
Factor X and its deficiency states
Haemophilia, 1997Summary. Factor X is one of the vitamin‐K‐dependent serine proteases. As a result of its position at the convergence of the intrinsic and extrinsic pathways of the clotting cascade, it plays a crucial role in blood coagulation. Factor X interacts with components of both pathways of coagulation, leading to its activation and the formation of the ...
openaire +2 more sources
One Missense Mutation in the Factor X Gene Causing Factor X Deficiency—Factor X Kanazawa
International Journal of Hematology, 2001We investigated the molecular basis of factor X deficiency in a Japanese patient whose factor X activity and antigen level were 45% and 50% of normal control values, respectively. All exons and intron/exon junctions of the factor X gene were studied using a strategy combining polymerase chain reaction (PCR) amplification and nonradioactive single ...
E, Morishita +8 more
openaire +2 more sources
A NEW VARIANT OF FACTOR X DEFICIENCY (FACTOR X ROMA).
Thrombosis and Haemostasis, 1987A 13 years-old-girl was admitted in our Hospital for a large muscle hematoma of left psoas. At age 3 she had a severe tonsillar bleeding following angina. Afterwards she suffered from easy bruisability and recurrent epistaxis. Prothrombin time (PT) was slightly prolonged (14.7 sec, control 12 sec, INR 1.5), while a more marked prolongation in aPTT was ...
V De Stefano +3 more
openaire +1 more source