Results 21 to 30 of about 4,918,610 (234)

Ischemic stroke and dose adjustment of oral Factor Xa inhibitors in patients with atrial fibrillation [PDF]

open access: yes, 2023
Background Oral Factor Xa inhibitors for the prevention of stroke in atrial fibrillation require dose adjustment based on certain clinical criteria, but the off-label use of the reduced doses is common. Methods
Marsch, Armin   +9 more
core   +2 more sources

Thrombocytopenia induced by dabigatran: two case reports

open access: yesBMC Neurology, 2017
Background Vitamin K inhibitors (e.g. warfarin) and indirect thrombin inhibitors (e.g. heparin) are widely used to prevent thromboembolic disorders (e.g. myocardial infarction, venous thromboembolism, and stroke).
Hyun Goo Kang   +3 more
doaj   +1 more source

Bivalirudin in combination with heparin to control mesenchymal cell procoagulant activity. [PDF]

open access: yesPLoS ONE, 2012
Islet and hepatocyte transplantation are associated with tissue factor-dependent activation of coagulation which elicits instant blood mediated inflammatory reaction, thereby contributing to a low rate of engraftment.
Xavier Stephenne   +7 more
doaj   +1 more source

Resolution of a warfarin and dabigatran-resistant left atrial appendage thrombus with apixaban

open access: yesJournal of Arrhythmia, 2016
The majority of embolisms associated with atrial fibrillation (AF) are from the left atrial appendage (LAA). To treat the existing thrombus, warfarin and novel anticoagulants have been used.
Yosuke Miwa   +5 more
doaj   +1 more source

Improved efficacy/safety profile of factor XIa inhibitor BMS‐724296 versus factor Xa inhibitor apixaban and thrombin inhibitor dabigatran in cynomolgus monkeys

open access: yesResearch and Practice in Thrombosis and Haemostasis, 2021
Background Inhibition of activated factor XI (FXIa) is a promising antithrombotic drug target. BMS‐724296 is a selective, reversible, small‐molecule inhibitor of human FXIa (Ki 0.3 nM). Objectives This study assessed effects of BMS‐724296 versus standard‐
Pancras C. Wong, Mimi L. Quan
doaj   +1 more source

Molecular modeling study of protein-tyrosine kinases and Factor Xa for rational inhibitor design.

open access: yes, 1999
Molecular modeling study of protein-tyrosine kinases and Factor Xa for rational inhibitor ...
Yasheen. Zhou (7979243)
core   +3 more sources

PRISMA XA Checklist and Diagram

open access: yes, 2021
Prisma Checklist for Factor Xa Inhibitor For Venous Thromboembolism Management In Patient With Cancer: A Sysytematic Review And Meta ...
Makhyan Jibril Al Farabi (7840016)
core   +1 more source

Avances en el tratamiento del tromboembolismo pulmonar agudo [PDF]

open access: yesRevista SOCAMPAR, 2017
Resume: We present a case of a 78-year-old male patient with a personal history of urothelial carcinoma, squamous cell carci- noma of the larynx and colon adenocarcinoma, who came to the emergency room because for about 3 months he had cough with ...
Peña Durán A
doaj  

Clinical implication of monitoring rivaroxaban and apixaban by using anti-factor Xa assay in patients with non-valvular atrial fibrillation

open access: yesJournal of Arrhythmia, 2016
Background: Although patients taking non-vitamin K antagonist oral anticoagulants (NOACs) do not require routine coagulation monitoring, high-risk patients require monitoring to assess pharmacodynamics.
Kozue Ikeda, MD, Hideaki Tachibana, MD
doaj   +1 more source

Factor Xa cleavage of tissue factor pathway inhibitor is associated with loss of anticoagulant activity [PDF]

open access: yes, 1998
Tissue factor : factor VIIa induced activation of blood coagulation is inhibited by the complex between factor Xa and tissue factor pathway inhibitor (factor Xa : TFPI).
Hemker, H. Coenraad   +13 more
core   +1 more source

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