Results 171 to 180 of about 14,789,955 (251)

A Drug‐Gated, Modular STAb‐T Immunotherapy With External Control

Advanced Science, EarlyView.
Engineered STAb‐TON cells act as programmable living factories that continuously secrete inactive antibody modules, which assemble extracellularly into a functional T cell engager only upon small‐molecule administration. This externally controlled platform enables reversible, on‐demand regulation of antitumor immunity, establishing a new paradigm for ...
Susana Luengo‐Arias, Carmen Domínguez‐Alonso, Ivana Zagorac, Antonio Tapia‐Galisteo, Eva García‐Veros, Laura Rubio‐Pérez, Marina Gómez‐Rosel, Patricia Fuentes, Patricia Hernández‐López, Óscar Aguilar‐Sopeña, Laura Almagro‐Puente, Sonia Martínez‐González, Lucía Cañizares‐Moscato, María Rivas‐Sánchez, Belén Blanco, Ángel Ramírez‐Fernández, Laura Díez‐Alonso, Carmen Blanco‐Aparicio, Javier Arroyo‐Ródenas, Jorge Martínez‐Torrecuadrada, María L. Toribio, Pedro Roda‐Navarro, Anaïs Jiménez‐Reinoso, Luis Álvarez‐Vallina   +23 more
wiley   +1 more source

A model of zymogen factor XII: insights into protease activation. [PDF]

Blood Adv
Shamanaev A, Ma Y, Ponczek MB, Sun MF, Cheng Q, Dickeson SK, McCarty OJT, Emsley J, Mohammed BM, Gailani D.   +9 more
europepmc   +1 more source

Severe Prekallikrein Deficiency Associated with Low Level of Factor XII: A Case Report. [PDF]

Iran J Pathol, 2021
Shahbazi M, Ahmadinejad M, Fakhrzadegan S.   +2 more
europepmc   +1 more source

Engineered Cyanobacteria‐Hydrogel Microecological System for Oxygen Reprogramming Synergizes Immunomodulation With Anabolism in Osteoarthritis Therapy

Advanced Science, EarlyView.
An injectable cyanobacteria‐laden hydrogel enables light‐dependent oxygen metabolism engineering for osteoarthritis therapy. Photosynthetic oxygen release under red light irradiation suppresses synovial inflammation via HIF‐1α inhibition and M2 macrophage polarization, while respiratory oxygen consumption in darkness stabilizes chondrocyte HIF‐1α to ...
Lerong Yang, Chong Shen, Hongjun Huang, Siyi Liu, Zeyu Huang, Licheng Xi, Huan Cao, Li Zheng, Zainen Qin   +8 more
wiley   +1 more source

Factor XII deficiency in asymptomatic Saudi population: A retrospective cohort study. [PDF]

Saudi J Biol Sci, 2021
Alqahtany FS, Algahtani FH, Alshebly MM, Albegamy TS, Alghamdi ES, Alnakhli MA, Madkhaly FM, Alharbi AA, Alqahtani NA.   +8 more
europepmc   +1 more source

From Magnetic Fibers to Paper Architectures: A Lightweight Strategy for Robust Low‐Frequency Microwave Absorption

Advanced Science, EarlyView.
A scalable process converts para‐aramid fibers into soft‐magnetic building blocks via micrometer‐thick Fe0.64Ni0.36 (Invar‐type) coatings. Assembled into paper, they form a hierarchical conductive network whose tunable permeability enables thin, lightweight microwave absorption in the low‐frequency (S‐band) regime.
You Wu, Yanlong Li, Haitong Sun, Tao Liu, Kehai Liu, Kaihui Liu, Zhaoxia Sun, Wenbo Ju   +7 more
wiley   +1 more source

Critical limb ischemia leading to amputation as a presentation of acquired hemophilia A with congenital factor XII deficiency: a case report. [PDF]

Int J Surg Case Rep
Van Nut L, Bao DD, Le Cuong B, Van Quang N.   +3 more
europepmc   +1 more source

Peptide Macrocycle Inhibitor of Coagulation Factor XII with Subnanomolar Affinity and High Target Selectivity.

Journal of Medicinal Chemistry, 2017
S. Middendorp, Jonas Wilbs, Claudia Quarroz, S. Calzavarini, A. Angelillo-Scherrer, C. Heinis   +5 more
semanticscholar   +1 more source

Repurposing FDA‐Approved Drugs to Inhibit Fungal PPTases for Broad‐Spectrum Synergy

Advanced Science, EarlyView.
Fungal secondary metabolites serve as crucial virulence effectors; however, the potential of their biosynthetic pathways as antifungal targets remains inadequately comprehended. Repurposed FDA‐approved drugs inhibit fungal PPTase (essential for secondary metabolism) in vivo.
Zili Song, Can Zhao, Qiaoling Wang, Hongjiao Zhang, Xiao Liu, Linqi Wang, Michael Bromley, Wen‐Bing Yin   +7 more
wiley   +1 more source

Editorial: Proceedings of KININ2018CLE, Cleveland, Ohio, June 18-20, 2018: A Compendium of the Presentations

Frontiers in Medicine, 2019
Alvin H. Schmaier, Marvin T. Nieman, Keith R. McCrae, Sadashiva Karnik, Joao Bosco Pesquero   +4 more
doaj   +1 more source