Results 21 to 30 of about 9,704 (246)

Inherited Factor XII Deficiency—What Is the Real Concern for Neuroanesthesiologist: Bleeding or Clotting

Journal of Neuroanaesthesiology and Critical Care, 2020
Factor XII deficiency is a rare disorder that can complicate the perioperative management of a patient. Factor XII plays an important role in the activation of intrinsic pathway of coagulation; the deficiency, therefore, results in prolongation of ...
Mouleeswaran Sundaram, Sonia Bansal, Rohini M. Surve   +2 more
doaj   +1 more source

Factor XI Deficiency Alters the Cytokine Response and Activation of Contact Proteases during Polymicrobial Sepsis in Mice. [PDF]

PLoS ONE, 2016
Sepsis, a systemic inflammatory response to infection, is often accompanied by abnormalities of blood coagulation. Prior work with a mouse model of sepsis induced by cecal ligation and puncture (CLP) suggested that the protease factor XIa contributed to ...
Charles E Bane, Ivan Ivanov, Anton Matafonov, Kelli L Boyd, Qiufang Cheng, Edward R Sherwood, Erik I Tucker, Stephen T Smiley, Owen J T McCarty, Andras Gruber, David Gailani   +10 more
doaj   +1 more source

Skeletal prognathism with factor XII deficiency causing complications in perioperative management: A case report

Advances in Oral and Maxillofacial Surgery, 2021
A 21-year-old man with mandibular prognathism was referred to Tokyo Medical University Hospital. The patient was diagnosed as having skeletal prognathism.
Hayato Hamada, Yoko Kawase-Koga, On Hasegawa, Masato Watanabe, Daichi Chikazu   +4 more
doaj   +1 more source

Factor XII Deficiency

RGUHS Journal of Medical Sciences, 2017
Acase of Factor XII deficiency which was incidentally recognized in a child who presented with purpuric lesions is reported ...
Baldua V, Kadam P, Castellino N, Castellino S, Saste S, Agarwal N   +5 more
openaire   +1 more source

The complex role of kininogens in hereditary angioedema

Frontiers in Allergy, 2022
Human high molecular weight kininogen (HK) is the substrate from which bradykinin is released as a result of activation of the plasma “contact” system, a cascade that includes the intrinsic coagulation pathway, and a fibrinolytic pathway leading to the ...
Allen P. Kaplan, Kusumam Joseph, Berhane Ghebrehiwet   +2 more
doaj   +1 more source

Mechanisms involved in hereditary angioedema with normal C1-inhibitor activity

Frontiers in Physiology, 2023
Patients with the inherited disorder hereditary angioedema (HAE) suffer from episodes of soft tissue swelling due to excessive bradykinin production.
Aleksandr Shamanaev, S. Kent Dickeson, Ivan Ivanov, Maxim Litvak, Mao-Fu Sun, Sunil Kumar, Quifang Cheng, Priyanka Srivastava, Tracey Z. He, David Gailani   +9 more
doaj   +1 more source

Factor XII (Hageman) Levels in Women with Recurrent Pregnancy Loss

Journal of Pregnancy, 2014
Objective. To evaluate factor XII levels in women with recurrent pregnancy loss (RPL) in a tertiary referral hospital. Methods. Women who were referred to our hospital for two consecutive abortions or three abortions in between 2007 and 2013 were ...
A. Seval Ozgu-Erdinc, Cihan Togrul, Ayla Aktulay, Umran Buyukkagnici, Elif Gul Yapar Eyi, Salim Erkaya   +5 more
doaj   +1 more source

Alleviation of secondary brain injury, posttraumatic inflammation, and brain edema formation by inhibition of factor XIIa

Journal of Neuroinflammation, 2017
Background Traumatic brain injury (TBI) is a devastating neurological condition and a frequent cause of permanent disability. Posttraumatic inflammation and brain edema formation, two pathological key events contributing to secondary brain injury, are ...
Sarah Hopp, Marc W. Nolte, Christian Stetter, Christoph Kleinschnitz, Anna-Leena Sirén, Christiane Albert-Weissenberger   +5 more
doaj   +1 more source

Fatal acquired coagulation factor V deficiency after hepatectomy for advanced hepatocellular carcinoma as a possible immune checkpoint inhibitor-related adverse event: a case report

Surgical Case Reports, 2023
Background Atezolizumab plus bevacizumab therapy was recently introduced as the first line for unresectable advanced hepatocellular carcinoma (HCC), but immune-related adverse events (IrAEs) due to atezolizumab are a great concern.
Shintaro Arakaki, Shinichiro Ono, Futoshi Kawamata, Shinichiro Ishino, Yasunori Uesato, Tomo Nakajima, Yukiko Nishi, Satoko Morishima, Shingo Arakaki, Tatsuji Maeshiro, Masayoshi Souri, Akitada Ichinose, Hiroaki Masuzaki, Mitsuhisa Takatsuki   +13 more
doaj   +1 more source

Impact of Deficiency of Intrinsic Coagulation Factors XI and XII on Ex Vivo Thrombus Formation and Clot Lysis

TH Open, 2019
The contributions of coagulation factor XI (FXI) and FXII to human clot formation is not fully known. Patients with deficiency in FXI have a variable mild bleeding risk, whereas FXII deficiency is not associated with bleeding.
José W. P. Govers-Riemslag, Joke Konings, Judith M. E. M. Cosemans, Johanna P. van Geffen, Bas de Laat, Johan W. M. Heemskerk, Yesim Dargaud, Hugo ten Cate   +7 more
doaj   +1 more source