Results 21 to 30 of about 146,062 (286)

Donor-to-recipient transmission of factor XII deficiency by orthotopic liver transplantation [PDF]

open access: yesBaylor University Medical Center Proceedings, 2019
Hussien Elsiesy, Mohamed Abdelfattah
exaly   +2 more sources

Inherited Factor XII Deficiency—What Is the Real Concern for Neuroanesthesiologist: Bleeding or Clotting

open access: yesJournal of Neuroanaesthesiology and Critical Care, 2020
Factor XII deficiency is a rare disorder that can complicate the perioperative management of a patient. Factor XII plays an important role in the activation of intrinsic pathway of coagulation; the deficiency, therefore, results in prolongation of ...
Mouleeswaran Sundaram   +2 more
doaj   +1 more source

Factor XI Deficiency Alters the Cytokine Response and Activation of Contact Proteases during Polymicrobial Sepsis in Mice. [PDF]

open access: yesPLoS ONE, 2016
Sepsis, a systemic inflammatory response to infection, is often accompanied by abnormalities of blood coagulation. Prior work with a mouse model of sepsis induced by cecal ligation and puncture (CLP) suggested that the protease factor XIa contributed to ...
Charles E Bane   +10 more
doaj   +1 more source

Skeletal prognathism with factor XII deficiency causing complications in perioperative management: A case report

open access: yesAdvances in Oral and Maxillofacial Surgery, 2021
A 21-year-old man with mandibular prognathism was referred to Tokyo Medical University Hospital. The patient was diagnosed as having skeletal prognathism.
Hayato Hamada   +4 more
doaj   +1 more source

Aortic valve replacement and ventricular septal defect repair in factor XII deficiency: An anesthetic challenge

open access: yesSaudi Journal of Anaesthesia, 2019
Swapnil Verma   +3 more
doaj   +2 more sources

Mechanisms and regulation of the polyphosphate/factor XII-driven contact system in thrombosis and hemostasis [PDF]

open access: yes, 2016
Blood coagulation leading to fibrin formation is essential to prevent loss of blood (hemostasis), but can also contribute to occlusion of vessels (thrombosis).
Labberton, Linda
core   +1 more source

Mechanism and therapy of hereditary angioedema typ III and role of the contact system in inflammatory diseases [PDF]

open access: yes, 2014
Combinations of proinflammatory and procoagulant reactions are associated with a variety of disorders affecting the cardiovascular system. Vascular leakage contributes to the pathology of conditions such as, sepsis, allergy and anaphylactic reactions ...
Björkqvist, Jenny
core   +1 more source

Inhibitors in Patients with Congenital Bleeding Disorders Other Than Hemophilia [PDF]

open access: yes, 2017
The most worrying complication of replacement therapy for severe hemophilia A and B is currently the occurrence of inhibitory alloantibodies against infused factor VIII and factor IX, respectively.
Franchini, Massimo   +6 more
core   +1 more source

The complex role of kininogens in hereditary angioedema

open access: yesFrontiers in Allergy, 2022
Human high molecular weight kininogen (HK) is the substrate from which bradykinin is released as a result of activation of the plasma “contact” system, a cascade that includes the intrinsic coagulation pathway, and a fibrinolytic pathway leading to the ...
Allen P. Kaplan   +2 more
doaj   +1 more source

Mechanisms involved in hereditary angioedema with normal C1-inhibitor activity

open access: yesFrontiers in Physiology, 2023
Patients with the inherited disorder hereditary angioedema (HAE) suffer from episodes of soft tissue swelling due to excessive bradykinin production.
Aleksandr Shamanaev   +9 more
doaj   +1 more source

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