Results 61 to 70 of about 9,704 (246)

Characterization of the thrombin generation potential of leukemic and solid tumor cells by calibrated automated thrombography

Haematologica, 2012
Background Thrombin, the final enzyme of blood coagulation, is a multifunctional serine protease also involved in the progression of cancer. Tumor cells may activate blood coagulation proteases through the expression of procoagulant activities.
Marina Marchetti, Erika Diani, Hugo ten Cate, Anna Falanga   +3 more
doaj   +1 more source

Neurological, Neurodevelopmental and Treatment Outcomes in Patients With Pyruvate Dehydrogenase Complex Deficiency

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aim of this study was to characterize intellectual and motor function, neurological features including epilepsy, treatment response, and adaptive behavior in patients with pyruvate dehydrogenase complex deficiency (PDCD) in Sweden.
Antri Savvidou, Colin Reilly, Kalliopi Sofou, Sofia Ygberg, Erik A. Eklund, Karin Naess, Niklas Darin   +6 more
wiley   +1 more source

Cerebrospinal Fluid Over Plasma Links Analytes to Cognitive Decline in Older Adults at Risk for Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify inflammatory analytes in cerebrospinal fluid (CSF) and plasma associated with cognitive decline in cognitively normal (CN) older adults at risk for Alzheimer's disease (AD). Methods In a longitudinal study of 118 CN older adults (65–80 years, 54% APOE ε4, 26% preclinical AD), 1331 CSF and 1501 plasma analytes were ...
Jagan A. Pillai, Audrey Zhu, Chunxuan Ma, Ming Wang, Yifan Yang, Lynn M. Bekris, Maria Khrestian, Frank P. DiFilippo, Mikhail Nasrallah, Aaron Burberry, James B. Leverenz, Yuan Hou, Feixiong Cheng, Stephen M. Rao   +13 more
wiley   +1 more source

Proteins of the Hageman Factor System in an Inflammatory Reaction in the Acute Period of Severe Brain Injury

Общая реаниматология, 2010
Objective: to study the time course of changes and an association of contact factors and their inhibitors with the global values of hemocoagulation, fibrinolysis, and inflammatory reactants in acute severe brain injury (SBI) in order to deepen notions of
T. I. Borshchikova, N. N Yepifantseva, Yu. A. Churlyaev, N. V., Nikiforova, Ya. A. Zhukova, A. I. Pirogova, Ye. A. Nikitina, A. V. Yekimovskikh   +7 more
doaj   +1 more source

Is an Apple an Orange? A Large Language Model Benchmark for Candidate Term Extraction and Subclass Decisions Against Upper Ontologies in Engineering and Materials Science

Advanced Engineering Materials, EarlyView.
Building machine‐readable vocabularies for materials science is slow, expert‐driven work. This study benchmarks 13 large language models on two of its first steps: finding candidate terms in engineering articles and deciding where they belong in a class hierarchy.
Thomas Bjarsch, Maximilian Holland, Klaus Drechsler, Johannes Schilp   +3 more
wiley   +1 more source

Reversible Calcium Alloying on Bulk and Indium (Sub)‐Micro Negative Electrodes for Calcium‐Based Batteries

Advanced Functional Materials, EarlyView.
Description: Indium metal serves as a reversible calcium‐alloying negative electrode. By transitioning from planar electrodes to powders and (sub‐)micron indium particles, the specific surface area is increased, improving the areal capacity density and cycling stability for calcium‐based batteries.
Wouter Monnens, Robert Markowski, Zhenyu Zhou, Claude Poleunis, Livia Grgurić, Jan Bitenc, Pingping Tan, Han‐Hung Hsu, Alexandru Vlad, Koen Binnemans, Jan Fransaer   +10 more
wiley   +1 more source

Chronic thromboembolic pulmonary hypertension is a clot you cannot swat

Journal of Vascular Surgery Cases and Innovative Techniques, 2019
A 49-year-old man with progressive dyspnea on exertion and a remote history of syncope presented with hypotension and acute right ventricular failure, and was ultimately diagnosed with acute pulmonary embolism.
G. Jay Bishop, MD, FACP, FSVM, RPVI, Joshua Gorski, MD, Daniel Lachant, DO, Scott J. Cameron, MD, PhD, RPVI, FSVM, FACC   +3 more
doaj   +1 more source

Self‐Healing Hydrogel‐Enabled Modular Assembly of Bilayered Skin Construct for Hair Follicle Regeneration

Advanced Healthcare Materials, EarlyView.
Self‐healing assembly of two cell‐laden hydrogel layers creates a biomimetic skin construct that restores both dermal and epidermal functions, resulting in accelerated wound healing and enhanced hair follicle regeneration in a full‐thickness skin wound model. ABSTRACT Alopecia remains a pervasive clinical challenge, largely owing to the limited ability
JaeWook Park, Su Yong Kim, MinSu Jeong, Beom Joon Kim, Shin Hyuk Kang, Won‐Gun Koh   +5 more
wiley   +1 more source

Pregnancy complicated by Factor XII deficiency: a case report and literature review

The Journal of Maternal-Fetal & Neonatal Medicine
Background Factor XII deficiency, a rare inherited coagulation disorder, typically presents with isolated prolonged activated partial thromboplastin tim without spontaneous bleeding.
Yunyi Su, XueMei Wu, Xian Wu, Yaojie Li, Aijie Xie, Xia Jiang, XinE Zhou, Xia Yu, Xiaoqin Gan   +8 more
doaj   +1 more source

Factor XII Deficiency in ECMO Patients

Blood, 2019
Background: Extracorporeal membrane oxygenation (ECMO) for cardiopulmonary support of critically ill patients is used frequently in the pediatric and adult population. Although a lifesaving modality, it is burdened with high morbidity and mortality as a result of hematologic complications (Dalton, et al. Am J Respir Crit Care Med. 2017).
Katherine Regling, Sarah Ramiz, Meera B. Chitlur   +2 more
openaire   +1 more source