Results 141 to 150 of about 72,175 (268)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

[Atrial fibrillation in primary care: Towards a proactive risk-based model focused on early prevention]. [PDF]

Aten Primaria
Clua-Espuny JL, Muria-Subirats E, Gentille-Lorente DI.   +2 more
europepmc   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

[Prevalence and severity of dental fluorosis and associated environmental and behavioral factors in children from a rural population]. [PDF]

Rev Cient Odontol (Lima)
Rodriguez-Landauro AJ, Marín-Sánchez O, Marín-Machuca O, Campos-Campos KJ.   +3 more
europepmc   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

[Challenges in primary health care: a look from the past to the future]. [PDF]

Aten Primaria
León-Gómez BB, Seda-Gombau G, Torán-Monserrat P.   +2 more
europepmc   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

[Work-Family Conflict and its Impact on Working Women's Health: A Systematic Review]. [PDF]

Aten Primaria
García-Rodríguez I, Gómez-Salgado J, Prieto-Callejero B, Fagundo-Rivera J, Khoury-Moreno LE, García-Iglesias JJ.   +5 more
europepmc   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

[Response to comment on the article "Incidence and factors associated with delirium in an Emergency Department"]. [PDF]

Rev Med Inst Mex Seguro Soc
Ayón-Aguilar J, Serrano-Vértiz L, Quiroz-Lara FV, Torres-Macotela M.   +3 more
europepmc   +2 more sources