Results 151 to 160 of about 72,175 (268)

[Clinical activity and validation of the disability disc in inflammatory bowel disease]. [PDF]

Rev Med Inst Mex Seguro Soc
Plomozo-Román R, Lozano-García I, Martínez-Torres H, Torres-Mendoza BM, Maldonado-Rodríguez R, Aguayo-Villaseñor JF, Jaramillo-Buendía C, Gutiérrez-Sevilla JE.   +7 more
europepmc   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

[Environmental medicine and AI, migration, and emerging and reemerging diseases in Mexico]. [PDF]

Rev Med Inst Mex Seguro Soc
Rivera-Silva G, Moreno-Treviño MG, Garza-Martínez R.   +2 more
europepmc   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

[Factors associated with cardiometabolic disease screening in older adults in the Peruvian AmazonFatores associados ao rastreamento de doenças cardiometabólicas em pessoas idosas da Amazônia peruana]. [PDF]

Rev Panam Salud Publica
Ñaña-Cordova AM, Macavilca-Toribio MA, Reyna-Ruiz VL, Oria-Morales M, Gonzales-Espinoza AJ, Parodi JF, Camacho-Caballero K, Runzer-Colmenares FM.   +7 more
europepmc   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

[The risk of choosing a residency in Health Sciences: a narrative review of key factors in decision-making] [PDF]

Rev Fac Cien Med Univ Nac Cordoba
García Dieguez M, Nardi M, Ladenheim R.
europepmc   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

[Management of pseudoaneurysm associated with endovascular treatments at third level]. [PDF]

Rev Med Inst Mex Seguro Soc
Páez-Sánchez MM, Calderón-Llamas MÁ, Nuño-Escobar C, Guerrero-Jauregui JÁ, Rodríguez-Ortega HA, Ramírez-Plascencia JI, Pedro Hugo PH, Olivas-Flores EM.   +7 more
europepmc   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source