Results 191 to 200 of about 72,175 (268)

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

[Colonisation or early invasion? Disseminated aspergillosis after bronchial isolation of <i>Aspergillus fumigatus</i> in a heart transplant recipient]. [PDF]

Rev Esp Quimioter
de-Gracia-Díaz JC, Hernández-Porto M, Alemán MR, Heredia-Frías A, Lecuona-Fernández M, Rodríguez-Díaz D.   +5 more
europepmc   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Incidence of surgical site infection surveillance in hysterectomies and related risk factors: a prospective cohort study. [PDF]

Rev Esp Quimioter
Rodríguez-Villar D, Cárdenas-Soriano MP, Climent-Martínez N, Pedraza-Flechas AM, Rodríguez-Villar S, Zamorano-Méndez P, Villar-Del-Campo MC, SanRomán-Montero JM, Durán-Poveda M, Rodríguez-Caravaca G.   +9 more
europepmc   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

[Climate crisis and mental health: a scoping review eco-anxiety in latinamerican adults]. [PDF]

Rev Med Inst Mex Seguro Soc
Guarderas-Muñoz SJ, Carrera-Reyes C, Fuenmayor-González L.   +2 more
europepmc   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

[2027: A new year for a new epidemiological study of chronic obstructive pulmonary disease in Spain]. [PDF]

Open Respir Arch
Soriano JB, Miravitlles M, López-Campos JL, García-Río F, Ancochea J.   +4 more
europepmc   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

[Cardiovascular risk in adults of indigenous descent in Argentina: an analysis of the Second National Nutrition and Health Survey] [PDF]

Rev Fac Cien Med Univ Nac Cordoba
Awruch C, Solarz F, Pérez Bridoux F, Zamora MF, Mattig ME, Cruz CV, Tentoni N, Politi MT.   +7 more
europepmc   +1 more source