Results 181 to 190 of about 72,175 (268)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

[Early virological failure with long-acting cabotegravir/rilpivirine: description of two cases]. [PDF]

Rev Esp Quimioter
Pena-López MJ, Torres-Martel EG, Santana-Baez S, Bosch-Guerra X.   +3 more
europepmc   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Tuberculosis in the South America's homeless: a systematic review of social determinants, control strategies and health equity. [PDF]

Rev Esc Enferm USP
Ramos EM, Sisti CB, Lima SBA, Araújo ELL, Guerra LDDS, Polubriaginof C, Guimarães AMS.   +6 more
europepmc   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

[Knowledge and attitudes about social determinants of respiratory health in SEPAR members]. [PDF]

Open Respir Arch
Soriano JB, Almonacid C, Urrutia-Landa I, Perpiñá-Tordera M, por el Grupo Transversal Determinantes Sociales de la Salud Respiratoria, SEPAR.   +5 more
europepmc   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

[Social determinants of therapeutic adherence among users of the primary health care system's cardiovascular health program in ChileDeterminantes sociais da adesão terapêutica entre usuários do programa de saúde cardiovascular na atenção primária à saúde do Chile]. [PDF]

Rev Panam Salud Publica
Herrera Atton D, Olivi A, Reyes Cabrera P, García Ubillo V, Veloz Baeza A, Veintimilla Carrión KS, Sánchez Lagos S.   +6 more
europepmc   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

[Emotional and social well-being in the indigenous population of Latin America: A systematic review]. [PDF]

Aten Primaria
Cardenas-Tambo T, Cervantes-Henríquez ML.   +1 more
europepmc   +1 more source