Results 181 to 190 of about 15,654,533 (356)
, 2015 Programa de doctorado: Patología quirúrgica, reproducción humana y factores psicológicos y el proceso de ...
Hernández González, Lourdes Del Carmen
core
Tabula Rasa: Revista de Humanidades, 2009 En este texto se aborda el tema del cerebro que aprende, cuyo propósito es describir el proceso de aprendizaje del órgano pensante, la manera que se posibilita su desarrollo durante toda la vida a través de las numerosas conexiones sinápticas que se ...
Bertha Marlen Velásquez Burgos +2 more
doaj
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Predicción del parto pretérmino mediante la medición ecográfica de la longitud cervical
, 2009 Programa de Patología Quirúrgica, Reproducción Humana, Factores Psicológicos y el Proceso de ...
Barber Marrero, Miguel Ángel
core
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
¿Es la medicina regenerativa, la clave en el tratamiento de la osteoartritis?
Revista Colombiana de Medicina Física y Rehabilitación, 2012 Objetivo: evaluar la utilidad de la tecnología de regeneración de tejidos disponible y el uso de células madre autólogas en el tratamiento de lesiones resultantes de la osteoartritis degenerativa en el cartílago hialino de las articulaciones grandes ...
Wilder Ariosto Gómez Huertas +2 more
doaj
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source