Results 201 to 210 of about 15,171,266 (336)

[Perinatal process: mental health and couple support]. [PDF]

Aten Primaria
Medina Gamero A.
europepmc   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Correction: Age at menarche and chronological age as explanatory factors of BMI: a cross-sectional study among Peruvian adolescents. [PDF]

BMC Womens Health
Gálvez-Díaz NDC, Javier-Aliaga D, Casas-Gálvez C, Barreto-Espinoza LA, Saintila J, Calizaya-Milla YE.   +5 more
europepmc   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

[Planetary Health from a prevention and health promotion perspective]. [PDF]

Aten Primaria
Del Campo Giménez M, Gallor Bohórquez H, Egea-Ronda A, Camarelles Guillem F, Jiménez Ochando L.   +4 more
europepmc   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

[Social determinants of therapeutic adherence among users of the primary health care system's cardiovascular health program in ChileDeterminantes sociais da adesão terapêutica entre usuários do programa de saúde cardiovascular na atenção primária à saúde do Chile]. [PDF]

Rev Panam Salud Publica
Herrera Atton D, Olivi A, Reyes Cabrera P, García Ubillo V, Veloz Baeza A, Veintimilla Carrión KS, Sánchez Lagos S.   +6 more
europepmc   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

[Cardiovascular risk in adults of indigenous descent in Argentina: an analysis of the Second National Nutrition and Health Survey] [PDF]

Rev Fac Cien Med Univ Nac Cordoba
Awruch C, Solarz F, Pérez Bridoux F, Zamora MF, Mattig ME, Cruz CV, Tentoni N, Politi MT.   +7 more
europepmc   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source