Results 71 to 80 of about 4,323 (252)
Revista Portuguesa de Educação, 2018 Este estudo tem como objectivo identificar os determinantes da escolha educacional e apoia-se em dados primários obtidos através da aplicação de um questionário ao universo dos alunos que se inscreveram, pela primeira vez, no ano 2004, em cursos ...
Isabel Ribeiro
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Sociodemographic determinants and mortality of premature newborns in a medium and low-income population in Colombia, 2017-2019. [PDF]
Biomedica, 2023 Torres-Muñoz J +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Factors that affect career success of nurses who practice in assisted reproductive technology. [PDF]
Rev Lat Am Enfermagem, 2023 Li W, Honggui W, Hong P, Hong L.
europepmc +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
DETERMINANTES DE LA INFORMALIDAD LABORAL: UN ANÁLISIS PARA COLOMBIA
Revista Investigación & Desarrollo, 2014 La informalidad representa una alternativa de fuente de ingresos ante la falta de oportunidades que tienen las personas de obtener un empleo en el sector formal.
Raúl Quejada Pérez +2 more
doaj
Dependência no Idoso: Factores determinantes
, 2010 O objectdo deste trabalho de investigação foi determinar quais os factores determinantes que influenciam o grau de dependência nos idosos com suporte social formal. Partiu-se do pressuposto que este estudo permitirá uma intervenção atempada e preventiva/optimizadora desta condição tão frequente na população idoso e que tem implicações significativas na
openaire +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source