Results 71 to 80 of about 4,268 (252)
Revista Portuguesa de Educação, 2018 Este estudo tem como objectivo identificar os determinantes da escolha educacional e apoia-se em dados primários obtidos através da aplicação de um questionário ao universo dos alunos que se inscreveram, pela primeira vez, no ano 2004, em cursos ...
Isabel Ribeiro
doaj +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
Sociodemographic determinants and mortality of premature newborns in a medium and low-income population in Colombia, 2017-2019. [PDF]
Biomedica, 2023 Torres-Muñoz J +4 more
europepmc +1 more source
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
How phagocytic cells kill bacteria: Lessons from a professional killer
FEBS Open Bio, EarlyView.How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley +1 more source
Factors that affect career success of nurses who practice in assisted reproductive technology. [PDF]
Rev Lat Am Enfermagem, 2023 Li W, Honggui W, Hong P, Hong L.
europepmc +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
DETERMINANTES DE LA INFORMALIDAD LABORAL: UN ANÁLISIS PARA COLOMBIA
Revista Investigación & Desarrollo, 2014 La informalidad representa una alternativa de fuente de ingresos ante la falta de oportunidades que tienen las personas de obtener un empleo en el sector formal.
Raúl Quejada Pérez +2 more
doaj
Dependência no Idoso: Factores determinantes
, 2010 O objectdo deste trabalho de investigação foi determinar quais os factores determinantes que influenciam o grau de dependência nos idosos com suporte social formal. Partiu-se do pressuposto que este estudo permitirá uma intervenção atempada e preventiva/optimizadora desta condição tão frequente na população idoso e que tem implicações significativas na
openaire +1 more source
FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source