Results 51 to 60 of about 1,574 (297)

Factores de calidad de algunas frutas cultivadas en Colombia. [PDF]

, 1972
La ausencia de normas de clasificación de frutas en Colombia, motivó al Programa Nacional de Hortalizas y Frutales adelantar este trabajo en el cual se proponen los valores límites que podrían usarse en la clasificación de frutos cítricos, piña, aguacate
Ríos Castaño, Danilo, Camacho Bustos, Saul E.   +1 more
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Properties of the Methanol Soluble Factor Required by the Mink.

Experimental Biology and Medicine, 1950
SummaryThe methanol extract factor required by the mink has been found to be soluble in 90% phenol and insoluble in acetone, n-butanol and 3/4 saturated ammonium sulfate.Fish solubles contain this factor, but dried distillers solubles, dried whey, pork spleen, and hog intestinal mucosa were found to be inactive.The relationship between the methanol ...
S B, TOVE, R J, LALOR, C A, ELVEHJEM
openaire   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Diversidad fenotípica de veinte accesiones promisorias de mangos criollos y comerciales introducidas en Colombia

Biotecnología en el Sector Agropecuario y Agroindustrial
La alta variabilidad genética es una de las consecuencias de los procesos de adaptación de las especies ante factores abióticos y bióticos extremos, lo cual contribuye a asegurar su persistencia frente a posibles riesgos. Colombia tiene establecidos más
Martha del Pilar López Hernández , Angelica Piedad Sandoval Aldana, Jairo García Lozano, Jorge Alberto Valencia Montoya   +3 more
doaj   +1 more source

Evaluación del efecto de PH y solidos solubles del zumo de naranja agria Citrus aurantium en el curado de chuletas de borrego Ovis aries [PDF]

, 2022
Evaluar los efectos del pH y solidos solubles del zumo de naranja agria en el curado de chuletas de borrego.La investigación parte por el problema del desconocimiento de las propiedades funcionales y nutricionales de la naranja agria Citrus aurantium y ...
Quimbiulco Puma, Oscar Santiago
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Influencia de la temperatura en la composición de los racimos de Vitis vinifera L. cv Pinot Noir expuestos al este y al oeste, en distintos estados de madurez

RIA: Revista Investigaciones Agropecuarias, 2012
Los componentes de las bayas (peso, azúcares, ácidos, polifenoles) están influenciados por el microclima de la canopia y por el estado de madurez de éstas, entre otros factores.
M. GALLINA
doaj  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source