Results 91 to 100 of about 15,541,552 (290)

A Human Factors Validation of a Smart Autoinjector Accessory Designed to Improve Self-Injection Outcomes and User Confidence

open access: yesMedical Devices: Evidence and Research
Stephan Wegner,1 Jana Milenkovic,1 Anthony D Andre,2 Carson P Whitaker,2 Tobias Theiler1 1Ypsomed AG, Burgdorf, Switzerland; 2Interface Analysis Associates LLC, Saratoga, CA, USACorrespondence: Stephan Wegner, Ypsomed AG, Brunnmattstrasse 6, Burgdorf ...
Wegner S   +4 more
doaj  

Impacts of subway air particles on healthy adults: a randomized controlled trial in a Chinese city

open access: yesParticle and Fibre Toxicology
Background Subway systems reduce traffic congestion, air pollution, and carbon dioxide emissions in cities but the impacts of subway air pollution on the health of subway users remain obscure.
Yuan Sun   +15 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Human factors design methods review

open access: yes, 2003
This report describes the human factors (HF) design methods review that was conducted as part of work package 1.3. 2-Design methods review, and is part of work package 1,'Human Factors Integration for C4i Systems'. The overall aim of work package 1.3.
Stanton, Neville A.   +2 more
core   +1 more source

Cardiovascular Risk Factors Associated with Venous Thromboembolism

open access: yes, 2019
Importance: It is uncertain to what extent established cardiovascular risk factors are associated with venous thromboembolism (VTE). Objective: To estimate the associations of major cardiovascular risk factors with VTE, ie, deep vein thrombosis and ...
Emerging Risk Factors Collaboration
core  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Global, Regional, and National Burden of Nontraumatic Subarachnoid Hemorrhage: The Global Burden of Disease Study 2021 [PDF]

open access: yes
IMPORTANCE Nontraumatic subarachnoid hemorrhage (SAH) represents the third most common stroke type with unique etiologies, risk factors, diagnostics, and treatments.
Ilari Rautalin   +3 more
core   +1 more source

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