Results 51 to 60 of about 3,315,315 (285)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Between Documentary and Provocation. New Tendencies (not only) in Contemporary Polish Holocaust Literature [PDF]

open access: yesSlovo a Smysl, 2018
The Holocaust can be seen as a transnational crime, and a collective trauma of universal extension. Therefore national approaches could be seen only as an example out of many others.
Hans-Christian Trepte
doaj  

Pursuing Transparency through Science Courts [PDF]

open access: yes, 2000
[Excerpt] The frequency and magnitude of risks and benefits are facts. The acceptability of risks associated with particular benefits is not. In the best of all worlds, normative choices based on facts would be made directly by persons at risk.
Field, Thomas G., Jr.
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

The Post-Truth Era and Fake News

open access: yesمجلة الآداب
Post-Truth Era is a term used recently by The Oxford Dictionary and it deals with facts have no much importance in our current world. People show no interest to know the truth and they believe what match their interests and desires.
Farah Hasan, Sanaa Hassan
doaj   +1 more source

What Normative Facts Should Political Theory Be About? Philosophy of Science meets Political Liberalism [PDF]

open access: yes, 2020
Just as different sciences deal with different facts—say, physics versus biology—so we may ask a similar question about normative theories.
List, Christian, Valentini, Laura
core  

Portable extraction of partially structured facts from the web [PDF]

open access: yes, 2010
A novel fact extraction task is defined to fill a gap between current information retrieval and information extraction technologies. It is shown that it is possible to extract useful partially structured facts about different kinds of entities in a broad
Jones, Gareth J.F.   +3 more
core   +4 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Has Latour Real-ly Unravelled the Real: The Journey from Laboratory Life to Down to Earth?

open access: yesLaw, Technology and Humans, 2020
This article traces Bruno Latour’s answer to the question ‘what is real?’ from Latour and Steve Woolgar in Laboratory Life: The Social Construction of Scientific Facts (1979) through to Latour in Down to Earth: Politics in the New Climate Change (2018 ...
Charles Lawson
doaj   +1 more source

Optimal Location and Parameter Setting of STATCOM Device Based PSO for Iraqi Grid Voltage Profile Enhancement and Power Losses Minimizing [PDF]

open access: yesEngineering and Technology Journal, 2019
The main goal of this work is to enhance the Voltage stability by using optimum location and parameters setting of STATCOM device. The parameters are the magnitude of the output voltage 𝑉𝑉𝑅 and the angle 𝛿𝑉𝑅, these parameters are taken to control the ...
Rashid Al-Rubayi, Mohammed Eesee
doaj   +1 more source

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