Results 51 to 60 of about 445,142 (296)
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
The Post-Truth Era and Fake News
مجلة الآدابPost-Truth Era is a term used recently by The Oxford Dictionary and it deals with facts have no much importance in our current world. People show no interest to know the truth and they believe what match their interests and desires.
Farah Hasan, Sanaa Hassan
doaj +1 more source
Suferințele tânărului Ghica [PDF]
Revista de Istorie și Teorie Literară, 2016 The subject of this presentation consists of three very little known works of the writer, economist and Liberal ideologist Ion Ghica (1816–1897), from 1835, 1838 and 1853, therefore, at least the first two ones written in his early youth.
Nicolae Mecu
doaj
Актуальні питання суспільних наук та історії медицини, 2020 The relevance of the research is determined by the need of philosoph- ical and humanitarian consideration of the diary-chronicle of Buko- vinian teacher and writer Ivan Bazhanskyi “War”. Exploring the textual features of the diary-chronicle genre
Antoniy MOYSEY, Yulia RUSNAK
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Dwie (anty)filozoficzne „gramatyki” Wittgensteina [Two (anti )philosophical grammars of Ludwig Wittgenstein] [PDF]
Analiza i Egzystencja, 2013 Wittgenstein is the author of two conceptions of “grammar”, that were meant to be tools of reaching the same goal: discrediting of the traditional, i.e. “metaphysical” questions of philosophy.
Adam Nowaczyk, Ewa Czesna
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The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Soft facts: Thinking practices and the architecture of reality
Daimon, 2013 It is common to criticize the idea of objectivity by claiming that we cannot make sense of any cognitive contact with the world that is not constituted by the very materials of our thinking, and to conclude that the idea must be abandoned and that the ...
Hilan Nissor Bensusan +1 more
doaj +1 more source