Results 101 to 110 of about 5,494,201 (309)
, 2011 Faculty award recipients: Academy of Effective Teaching / Jen-Chi Cheng -- Leadership in the Advancement of Teaching / Brien Bolin -- Excellence in Teaching / Kelly Anderson, Frank Rokosz -- Excellence in Creative Activity / Lynne Davis -- Excellence in ...
Faculty Senate
core
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
, 2008 Faculty award recipients: Academy of Effective Teaching / Timothy Quigley, Diane Scott, Larry Spurgeon -- Leadership in the Advancement of Teaching / Gamal Weheba -- Excellence in Teaching / Jen-Chi Cheng, Deborah Soles -- Excellence in Creative Activity
Faculty Senate
core
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Faculty award recipients: Young Faculty Scholar / Eylem Asmatulu -- Excellence in Online Teaching / Masud Chand -- Young Faculty Risk Taker / Abigail Devereaux -- Excellence in Teaching / Jody Fiorini -- Excellence in Research / Hyuck Kwon -- Excellence ...
Faculty Senate
core
, 2009 Faculty award recipients: Academy of Effective Teaching / M. Edwin Sawan -- Leadership in the Advancement of Teaching / LaDonna Hale -- Excellence in Teaching / Amy Drassen Ham, Richard LeCompte -- Excellence in Creative Activity / Darren DeFrain ...
Faculty Senate
core
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
, 2012 Faculty award recipients: Academy of Effective Teaching / Elizabeth Behrman, Natalie Grant -- Leadership in the Advancement of Teaching / Carolyn Shaw -- Excellence in Teaching / Doris Burgert, Preethika Kumar -- Excellence in Creative Activity / Julie ...
Faculty Senate
core
Archives Alive!: librarian-faculty collaboration and an alternative to the five-page paper
In the Library with the Lead Pipe, 2015 In brief: The short research paper is ubiquitous in undergraduate liberal arts education. But is this assignment type an effective way to assess student learning or writing skills?
Tom Keegan, Kelly McElroy
doaj
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source