Results 111 to 120 of about 8,579,941 (287)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Unleashing the Early Career Transition in Academic Medicine
Journal of Healthcare LeadershipDaryn H David Yale Child Study Center & Offices of Academic & Professional Development (OAPD) and Diversity, Equity, & Inclusion (ODEI), Yale School of Medicine, New Haven, CT, USACorrespondence: Daryn H David, Yale Child Study Center, Yale School of ...
David DH
doaj
ERNEST SOSA VE ENTELEKTÜEL ERDEMLER
Felsefe Dünyası, 2016 Modern/Çağdaş epistemolojinin kurucusu olarak kabul edilen çağdaş analitik filozoflardan Ernest Sosa, söz konusu epistemolojisinin en temel iki kavramından bir olan entelektüel erdem kavramını, temelcilik ve bağdaşımcılık arasındaki ‘ezeli’ sorunu ...
Kemal Batak
doaj
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
2017-18 Guide for Participants: Virginia Commonwealth University Peer Mentoring Program [PDF]
, 2017 The Peer Mentoring Program Guide for Participants provides information for both university faculty mentees and their faculty mentors to help establish and develop a productive mentoring relationship.
Pelco, Lynn E., Stanciu, Cristina
core +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Active-Learning Quality Improvement Training Curriculum for Faculty in Hospital Medicine [PDF]
, 2019 Background: There is a growing emphasis on teaching Quality Improvement (QI) to resident physicians and medical students. However, faculty with QI skills and knowledge is lacking at many academic medical centers.Active learning programs to improve ...
Burnett, Maria +3 more
core +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
What Determines Employment of Part-Time Faculty in Higher Education Institutions? [PDF]
, 2007 This study uses a cross-section national sample of four-year colleges and universities in the United States to examine the variation of part-time faculty employment.
Liu, Xiangmin, Zhang, Liang
core +1 more source