Results 131 to 140 of about 3,939,764 (351)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

University Engineering Faculty Depend on Scholarly Journals, Web Resources, and Face-to-Face Consultations to Help Them with Research. A Review of: Engel, D., Robbins, S., & Kulp, C. (2011). The information-seeking habits of engineering faculty. College & Research Libraries, 72(6), 548-567.

open access: yesEvidence Based Library and Information Practice, 2012
Objective – To study the information-seekingbehaviour of engineering faculty.Design – Online survey; Purposive sample.Setting – Engineering departments of 20 largepublic universities in various regions of theUnited States.Subjects – 903 engineering ...
Laura Newton Miller
doaj  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Assessment of Knowledge and Attitude among Faculty of Nursing Students Regarding Blood Donation [PDF]

open access: bronze, 2020
Asmaa Youssef Ezeldain   +3 more
openalex   +1 more source

Faculty Opinions recommendation of Directed evolution of APEX2 for electron microscopy and proximity labeling.

open access: yesFaculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2019
L. Trinkle-Mulcahy
semanticscholar   +1 more source

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