Results 51 to 60 of about 285,743 (339)

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Laser-Induced Fluorescence Spectroscopy in the Diagnosis of Tissue Hypoxia (Review)

Общая реаниматология, 2019
The aim of review is to discuss the results of studies on diagnosis of tissue hypoxia by laser-induced spectroscopy, as well as to identify promising trends and prospects of this technique for its further application in experimental and clinical medicine.
Anastasiya S. Babkina
doaj   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Reinforcement-Driven Spread of Innovations and Fads

, 2011
We propose kinetic models for the spread of permanent innovations and transient fads by the mechanism of social reinforcement. Each individual can be in one of M+1 states of awareness 0,1,2,...,M, with state M corresponding to adopting an innovation.
Anderson R M, Bailey N T J, Bass F M, Centola D, Centola D, D Volovik, Dall’Asta L, Dodds P S, Glass A J, Hayes B, Krapivsky P L Redner S Volovik D, Lohmann S, Maki D P, P L Krapivsky, Pérez-Reche F J, Rogers E M, S Redner, Vazquez F   +17 more
core   +1 more source

Publishing in top journals - a never-ending fad? [PDF]

, 2009
Starbuck is critical of faddishness, and with good reason. Fads may come, and fads may go, but go they must-or must they? We took at the relentless pressure to publish in the top journals of Management Studies.
Abrahamson, Abrahamson, Abrahamson, Barnard, Bunting, Carson, Chew, Clark, Gans, Huczynski, Jacqueline Kam, Johnson, Macdonald, Macdonald, MacRoberts, Micklethwait, Oliver, Phelan, Podsakoff, Ponzi, Price, Ronco, Rossner, Scarbrough, Starbuck, Starbuck, Starbuck, Strang, Stuart Macdonald, Thackray, Watson, Young   +31 more
core   +1 more source

Bacterial Production, Characterization and Protein Modeling of a Novel Monofuctional Isoform of FAD Synthase in Humans: An Emergency Protein?

Molecules, 2018
FAD synthase (FADS, EC 2.7.7.2) is the last essential enzyme involved in the pathway of biosynthesis of Flavin cofactors starting from Riboflavin (Rf). Alternative splicing of the human FLAD1 gene generates different isoforms of the enzyme FAD synthase ...
Piero Leone, M. Galluccio, A. Barbiroli, I. Eberini, M. Tolomeo, Flavia Vrenna, E. Gianazza, S. Iametti, F. Bonomi, C. Indiveri, M. Barile   +10 more
semanticscholar   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Vida interior. La Casa de Suecia. Madrid, años 50-60

RA. Revista de Arquitectura, 2023
Este artículo se centra en la vida interior de la Casa de Suecia, un edificio de Madrid proyectado por Mariano Garrigues en 1953, completado en 1956 y dañado irreparablemente en la actualidad.
Ismael Amarouch-García
doaj   +1 more source

Reduction of a-tocopherylquinone Model Compound With Various Reductant [PDF]

, 2001
In order to study the possibility of tranformation of a-tocopherylquinone (TQ) into a more oxidiseable compound and also to find out the recycling effect in the cells, an experiment was conducted by reducing the model compound 2-(3- hydroxy-3-methylbutyl)
Kohar, Indrajati
core  

FLEGT: Another ‘forestry fad’?

Environmental Science and Policy, 2018
There has been recent debate around the role of ‘fads’ in global conservation measures, and the lessons they hold for achieving desired conservation and development outcomes.
R. Rutt, Rodd Myers, Sabaheta Ramcilovic-Suominen, C. McDermott   +3 more
semanticscholar   +1 more source