Results 81 to 90 of about 403,724 (307)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Juan Carlos Onetti : La escritura con propósitos

Cuadernos LIRICO, 2013
We will consider the analysis of the writing processes in Juan Carlos Onetti’s novel Juntacadáveres(1964), focusing our work on documents, manuscripts and typescripts corrected by hand by the author himself. In the manuscripts where he drew up chapters 1
María Alejandra Alí
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Large-Scale Fading Characteristics and Models for Vehicle-to-Pedestrian Channel at 5-GHz

IEEE Access, 2019
Vehicle-to-Pedestrian (V2P) communication is essential to enable a reliable collision avoidance system for vehicles and vulnerable road users (VRUs). In order to develop a reliable communication system accurate channel models are required.
Ibrahim Rashdan, Fabian De Ponte Muller, Thomas Jost, Stephan Sand, Giuseppe Caire   +4 more
doaj   +1 more source

Method of Throughput Calculation for Microwave Link with Adaptive Modulation Under the Fading Conditions Inherent for Millimeter Waves

, 2023
Irina Stepanets
openalex   +2 more sources

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Multipath and Doppler Characterization of an Electromagnetic Environment by Massive MDT Measurements From 3G and 4G Mobile Terminals

IEEE Access, 2019
This paper describes an innovative approach to radio channel characterization in UMTS and LTE mobile networks. In place of traditional drive tests (DT), which employ a single test mobile, a massive collection of georeferenced radio measurements is made ...
Andrea Scaloni, Pasquale Cirella, Mauro Sgheiz, Riccardo Diamanti, Davide Micheli   +4 more
doaj   +1 more source

Approximate ergodic capacity of a class of fading 2-user 2-hop networks [PDF]

, 2012
Sang-Woon Jeon, Chien-Yi Wang, Michael Gastpar   +2 more
openalex   +1 more source