Results 111 to 120 of about 1,007 (134)

Real-time PCR assay for universal detection and quantitation of all five species of fowl adenoviruses (FAdV-A to FAdV-E)

Journal of Virological Methods, 2012
The present study describes the development of a SYBR Green based real-time polymerase chain reaction (real-time PCR) for detection and quantitation of all fowl adenovirus (FAdV) species. Primers were designed based on conserved nucleotide sequences within the 52K gene.
Ana Marek, Beatrice Grafl, Michael Hes   +2 more
exaly   +4 more sources

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A fowl adenovirus serotype 4 (FAdV-4) Fiber2 subunit vaccine candidate provides complete protection against challenge with virulent FAdV-4 strain in chickens

Veterinary Microbiology, 2021
Hypervirulent fowl adenovirus serotype 4 (FAdV-4)-induced hepatitis-hydropericardium syndrome (HHS) with high mortality causes huge economic losses to the poultry industry worldwide. However, commercially available vaccines against FAdV-4 infection remain scarce.
Dejing Yin, Kaigong Wang
exaly   +3 more sources

Phylogenetic Analyses of Fowl Adenoviruses (FAdV) Isolated in China and Pathogenicity of a FAdV-8 Isolate

Avian Diseases, 2017
Fowl adenoviruses (FAdVs) have a worldwide distribution and are associated with a variety of diseases, causing considerable economic losses to the poultry industry. We characterized 10 FAdVs isolated from China in 2015-2016 and assessed the pathogenicity of a FAdV-8 strain in specific-pathogen-free (SPF) chickens.
Ying-Chao Ren, Guozhong Zhang
exaly   +3 more sources

Characterization of a fowl adenovirus 9 (FAdV-9) early promoter and its application in generating dual expression FAdV-9s

Journal of Virological Methods, 2021
The CMV immediate early promoter from the EGFP expression plasmid pEGFP-N1 was replaced with the very left end of the fowl adenovirus 9 (FAdV-9) genome (ntds 73-574) to demonstrate and delineate the promoter function of this sequence. Expression of an EGFP ORF which replaced ORF1 and ORF2 demonstrated that the native promoter can drive down stream ...
Yanlong Pei, Peter J. Krell, Leonardo Susta, Éva Nagy   +3 more
openaire   +2 more sources

Complete genome sequence and pathogenicity analysis of a highly pathogenic FAdV-4 strain

Research in Veterinary Science, 2023
Fowl adenovirus serotype 4 (FAdV-4) is a double-stranded DNA virus that mainly infects broiler chickens and has caused huge economic losses to the poultry industry. Recently, an FAdV-4 strain, SDLC202009, the causative pathogen of hydropericardium-hepatitis syndrome (HHS) in Liaocheng, Shandong, was isolated from commercial laying hens and propagated ...
Kaili, Wang, Cheng, Liu, Xusheng, Du, Ye, Ma, Lele, Chen, Shenliang, Cao, Jianbiao, Lu, Yubao, Li, Zhenshu, Si   +8 more
openaire   +2 more sources

Fiber1, but not fiber2, is the essential fiber gene for fowl adenovirus 4 (FAdV-4)

Journal of General Virology, 2021
Fibre is the viral protein that mediates the attachment and infection of adenovirus to the host cell. Fowl adenovirus 4 (FAdV-4) possesses two different fibre trimers on each penton capsomere, and roles of the separate fibres remain elusive. Here, we attempted to investigate the function of FAdV-4 fibres by using reverse genetics approaches. Adenoviral
Xiaohui Zou, Yejing Rong, Xiaojuan Guo, Wenzhe Hou, Bingyu Yan, Tao Hung, Zhuozhuang Lu   +6 more
openaire   +2 more sources

FAdV-4 induce autophagy via the endoplasmic reticulum stress-related unfolded protein response

Veterinary Microbiology, 2022
Hydropericardium syndrome caused by the fowl adenovirus serotype 4 (FAdV-4) is prevalent disease in China with a high mortality rate. Many studies have demonstrated some viral infections to induce stress in the endoplasmic reticulum (ER). When the ER stress exceeds or persists, it activates autophagy, eventually triggering the onset of diseases ...
Haiying Ma, Yonghe Ding, Ke Du
exaly   +3 more sources

A novel recombinant chimeric Fiber-8a/8b-AD subunit vaccine provides complete protection against both FAdV-8a and FAdV-8b

Veterinary Microbiology
In recent years, outbreaks of fowl adenovirus (FAdV) in domestic chicken populations in China, particularly fowl adenovirus serotype 8 (FAdV-8), have attracted significant attention due to its role as a major causative agent of inclusion body hepatitis (IBH).
Wanzhe Yuan
exaly   +3 more sources

FAdV-4 infection induces selective mitochondrial autophagy

Veterinary Microbiology
Fowl adenovirus serotype 4 (FAdV-4) is an infectious pathogen that poses a significant threat to the poultry industry. It is widely disseminated globally and is characterized by high infection and mortality rates. Mitochondria, as multifunctional dual membrane-enclosed eukaryotic organelles, maintain cellular homeostasis through various mechanisms ...
Yujuan Niu
exaly   +3 more sources

Novel variant infectious bursal disease virus diminishes FAdV-4 vaccination and enhances pathogenicity of FAdV-4

Veterinary Microbiology
Infectious bursal disease virus (IBDV) caused an acute and highly contagious infectious disease characterized by severe immunosuppression, causing considerable economic losses to the poultry industry globally. Although this disease was well-controlled under the widely use of commercial vaccines in the past decades, the novel variant IBDV strains ...
Zhishan, Liang, Mei, Leng, Jiamin, Lian, Yazheng, Chen, Qi, Wu, Feng, Chen, Zhanxin, Wang, Wencheng, Lin   +7 more
openaire   +2 more sources